Background Increased peripheral inflammation has been consistently reported in patients
with major depressive disorder (MDD). However, only few studies have explored markers of …

Notwithstanding advances in understanding the pathophysiology of major depressive
disorder (MDD), no single mechanism can explain all facets of this disorder. An expanding …

Abstract Introduction Major Depressive Disorder (MDD) in accordance to the inflammatory
concept is associated with complex immunological disturbances in the central nervous …

Background Determining etiological factors and reviewing advances in diagnostic
modalities sensitive and specific to Major Depressive Disorder (MDD) is of importance in its …

Abstract Background Major Depressive Disorder (MDD) is a severe psychiatric disorder
whose pathological mechanisms are largely unknown. In the field of immuno-psychiatry …

Objective: Altered levels of peripheral inflammatory and proinflammatory cytokine markers
affect the different clinical stages of major depressive disorder (MDD). A concrete …

Importance Depression has been associated with alterations in neurotransmitters,
hormones, and inflammatory and neurodegenerative biomarkers, and biomarkers quantified …

Background Neuroinflammatory processes have been hypothesized to play a role in the
pathogenesis of psychiatric and neurological diseases. Studies on this topic often rely on …

Introduction Peripheral levels of inflammatory markers are elevated in major depressive
disorder (MDD). Selective serotonin reuptake inhibitors (SSRIs) affect levels of inflammatory …

BackgroundPeripheral low-grade inflammation in depression is increasingly seen as a
therapeutic target. We aimed to establish the prevalence of low-grade inflammation in …