Epithelial-mesenchymal plasticity in cancer progression and metastasis

W Lu, Y Kang - Developmental cell, 2019 - cell.com
Epithelial-to-mesenchymal transition (EMT) and its reversed process, mesenchymal-to-
epithelial transition (MET), are fundamental processes in embryonic development and tissue …

New insights into the mechanisms of epithelial–mesenchymal transition and implications for cancer

A Dongre, RA Weinberg - Nature reviews Molecular cell biology, 2019 - nature.com
Epithelial–mesenchymal transition (EMT) is a cellular programme that is known to be crucial
for embryogenesis, wound healing and malignant progression. During EMT, cell–cell and …

Epithelial–mesenchymal transition in development and cancer

DS Micalizzi, HL Ford - Future oncology, 2009 - Taylor & Francis
The epithelial–mesenchymal transition (EMT) is a critical developmental process from the
earliest events of embryogenesis to later morphogenesis and organ formation. EMT …

[HTML][HTML] Contribution of epithelial-mesenchymal transitions to organogenesis and cancer metastasis

K Campbell - Current opinion in cell biology, 2018 - Elsevier
The epithelial-to-mesenchymal transition (EMT) plays crucial roles during development, and
inappropriate activation of EMTs are associated with tumor progression and promoting …

Epithelial-mesenchymal transition: implications in cancer progression and metastasis

LR Gomes, LF Terra, MC Sogayar… - Current …, 2011 - ingentaconnect.com
During the past few years, Epithelial-Mesenchymal Transition (EMT) has emerged as one of
the most hot spots in clinical research. Its existence in human tumors can form the basis for …

EMT, cell plasticity and metastasis

CL Chaffer, BP San Juan, E Lim… - Cancer and Metastasis …, 2016 - Springer
Carcinoma cells that are induced to suppress their epithelial features and upregulate
mesenchymal gene expression programs acquire traits that promote an invasive and …

Epithelial-to-mesenchymal transition in cancer: complexity and opportunities

Y Zhang, RA Weinberg - Frontiers of medicine, 2018 - Springer
The cell-biological program termed the epithelial-to-mesenchymal transition (EMT) plays an
important role in both development and cancer progression. Depending on the contextual …

Epigenetic control of epithelial-mesenchymal-transition in human cancer

T Kiesslich, M Pichler… - … and clinical oncology, 2013 - spandidos-publications.com
Abstract Development and tissue homeostasis as well as carcinogenesis share the
evolutionary conserved process of epithelial-mesenchymal transition (EMT). EMT enables …

Epithelial-to-mesenchymal transition in tumor progression

E Prieto-García, CV Díaz-García, I García-Ruiz… - Medical Oncology, 2017 - Springer
The epithelial-to-mesenchymal transition (EMT) is a biological process in which a non-motile
epithelial cell changes to a mesenchymal state with invasive capacities. However, the EMT …

The ins and outs of the epithelial to mesenchymal transition in health and disease

MA Nieto - Annual review of cell and developmental biology, 2011 - annualreviews.org
The epithelial to mesenchymal transition (EMT) converts epithelial cells into migratory and
invasive cells and is a fundamental event in morphogenesis. Although its relevance in the …