Oxidative stress and inflammation: their role in the pathogenesis of peripheral artery disease with or without type 2 diabetes mellitus

SS Signorelli, N Katsiki - Current vascular pharmacology, 2018 - ingentaconnect.com
Peripheral Artery Disease (PAD), a common vascular disease, has been associated with
increased Cardiovascular (CV) morbidity and mortality as well as all-cause death. Type 2 …

Diabetes-versus smoking-related thrombo-inflammation in peripheral artery disease

T Alnima, RI Meijer, HMH Spronk, M Warlé… - Cardiovascular …, 2023 - Springer
Peripheral artery disease (PAD) is a major health problem with increased cardiovascular
mortality, morbidity and disabling critical limb threatening ischemia (CLTI) and amputation …

Pathophysiology of chronic peripheral ischemia: new perspectives

SS Signorelli, L Vanella, NG Abraham… - … advances in chronic …, 2020 - journals.sagepub.com
Peripheral arterial disease (PAD) affects individuals particularly over 65 years old in the
more advanced countries. Hemodynamic, inflammatory, and oxidative mechanisms interact …

[HTML][HTML] Peripheral artery disease, redox signaling, oxidative stress–basic and clinical aspects

S Steven, A Daiber, JF Dopheide, T Münzel… - Redox biology, 2017 - Elsevier
Reactive oxygen and nitrogen species (ROS and RNS, eg H 2 O 2, nitric oxide) confer redox
regulation of essential cellular signaling pathways such as cell differentiation, proliferation …

Oxidative stress and arterial dysfunction in peripheral artery disease

A Ismaeel, RS Brumberg, JS Kirk, E Papoutsi… - Antioxidants, 2018 - mdpi.com
Peripheral artery disease (PAD) is an atherosclerotic disease characterized by a narrowing
of the arteries in the lower extremities. Disease manifestations are the result of more than …

Oxidative stress in peripheral arterial disease (PAD) mechanism and biomarkers

SS Signorelli, S Scuto, E Marino, A Xourafa, A Gaudio - Antioxidants, 2019 - mdpi.com
Hemodynamic dysfunction mainly characterizes pathophysiology of peripheral arterial
disease (PAD) leading to chronic ischemia. Hemodynamic dysfunction is the origin of …

Pathophysiology of Peripheral Arterial Disease (PAD): a review on oxidative disorders

SS Signorelli, E Marino, S Scuto… - International Journal of …, 2020 - mdpi.com
Peripheral arterial disease (PAD) is an atherosclerotic disease that affects a wide range of
the world's population, reaching up to 200 million individuals worldwide. PAD particularly …

[HTML][HTML] Peripheral artery disease in patients with diabetes: Epidemiology, mechanisms, and outcomes

T Thiruvoipati, CE Kielhorn… - World journal of …, 2015 - ncbi.nlm.nih.gov
Peripheral artery disease (PAD) is the atherosclerosis of lower extremity arteries and is also
associated with atherothrombosis of other vascular beds, including the cardiovascular and …

Oxidative-stress-mediated arterial dysfunction in patients with peripheral arterial disease

L Loffredo, A Marcoccia, P Pignatelli… - European heart …, 2007 - academic.oup.com
Aims To investigate the existence of a relationship among flow-mediated dilation (FMD),
nitric oxide (NO), and oxidative stress in patients with peripheral arterial disease (PAD), and …

A rational connection of inflammation with peripheral arterial disease

J Li, JJ Li, Q Li, Z Li, HY Qian - Medical hypotheses, 2007 - Elsevier
Peripheral arterial disease (PAD) includes a wide range of manifestations in the lower limb,
from asymptomatic to symptomatic disease ranging from intermittent claudication to critical …