Toll-like receptors (TLRs) are pattern recognition receptors playing a fundamental role in
sensing microbial invasion and initiating innate and adaptive immune responses. TLRs are …

Toll-like receptors (TLRs) are sentinel receptors of the host innate immune system that
recognize conserved'pathogen-associated molecular patterns' of invading microbes …

Roles for Toll-like receptors (TLRs) are emerging in conditions such as sepsis syndrome,
systemic lupus erythromatosis, rheumatoid arthritis and asthma, suggesting that the …

Despite a decrease in mortality over the last decade, sepsis remains the tenth leading
causes of death in western countries and one of the most common cause of death in …

Abstract The Toll-like receptors (TLRs) are essential transmembrane signaling receptors of
the innate immune system that alert the host to the presence of a microbial invader. The …

Toll-like receptors (TLRs) are sensors of foreign microbial products, which initiate host
defense responses in all multicellular organisms examined to date. They are the target for …

Toll-like receptor 4 (TLR4), the signal-transducing molecule of the LPS receptor complex,
plays a fundamental role in the sensing of LPS from Gram-negative bacteria. Activation of …

The Toll-like receptors (TLRs) are a class of pattern recognition molecules with unique
functions in the innate and the acquired immune systems. The innate immune response has …

The innate immune system is essential for host defense and is responsible for early
detection of potentially pathogenic microorganisms. Upon recognition of microbes by innate …

Toll-like receptors (TLRs) recognise highly conserved molecular structures, collectively
known as pathogen-associated molecular patterns. In the past two decades, development …