High fat diet reduces the expression of miRNA‐29b in heart and increases susceptibility of myocardium to ischemia/reperfusion injury

EC Guedes, IB da Silva, VM Lima… - Journal of Cellular …, 2019 - Wiley Online Library
Several studies have shown the role of microRNAs (miRNAs) in myocardial dysfunction in
response to ischemia/reperfusion (I/R). In this study, we investigated the impact of high fat …

MicroRNA-30c-5p protects against myocardial ischemia/reperfusion injury via regulation of Bach1/Nrf2

M Sun, M Guo, G Ma, N Zhang, F Pan, X Fan… - Toxicology and Applied …, 2021 - Elsevier
MicroRNAs (miRNAs) are critical regulatory factors in myocardial ischemia/reperfusion (I/R)
injury. The miRNA miR-30c-5p has been reported as a key mediator in several myocardial …

MicroRNA-320 is involved in the regulation of cardiac ischemia/reperfusion injury by targeting heat-shock protein 20

XP Ren, J Wu, X Wang, MA Sartor, J Qian, K Jones… - Circulation, 2009 - Am Heart Assoc
Background—Recent studies have identified critical roles for microRNAs (miRNAs) in a
variety of cellular processes, including regulation of cardiomyocyte death. However, the …

miR-1 exacerbates cardiac ischemia-reperfusion injury in mouse models

Z Pan, X Sun, J Ren, X Li, X Gao, C Lu, Y Zhang… - PloS one, 2012 - journals.plos.org
Recent studies have revealed the critical role of microRNAs (miRNAs) in regulating cardiac
injury. Among them, the cardiac enriched microRNA-1 (miR-1) has been extensively …

Inhibition of miR-15 protects against cardiac ischemic injury

TG Hullinger, RL Montgomery, AG Seto… - Circulation …, 2012 - Am Heart Assoc
Rationale: Myocardial infarction (MI) is a leading cause of death worldwide. Because
endogenous cardiac repair mechanisms are not sufficient for meaningful tissue …

[HTML][HTML] Inhibition of microRNA-1 attenuates hypoxia/re-oxygenation-induced apoptosis of cardiomyocytes by directly targeting Bcl-2 but not GADD45Beta

C Zhai, G Tang, L Peng, H Hu, G Qian… - American journal of …, 2015 - ncbi.nlm.nih.gov
MicroRNAs are small non-coding RNAs that are able to regulate gene expression and play
important roles in some biological and pathological processes, including the myocardial …

MicroRNA-494 targeting both proapoptotic and antiapoptotic proteins protects against ischemia/reperfusion-induced cardiac injury

X Wang, X Zhang, XP Ren, J Chen, H Liu, J Yang… - Circulation, 2010 - Am Heart Assoc
Background—MicroRNAs (miRs) participate in many cardiac pathophysiological processes,
including ischemia/reperfusion (I/R)-induced cardiac injury. Recently, we and others …

Inhibition of miR-153 ameliorates ischemia/reperfusion-induced cardiomyocytes apoptosis by regulating Nrf2/HO-1 signaling in rats

W Hou, X Zhu, J Liu, J Map - Biomedical engineering online, 2020 - Springer
Background Previous in vitro studies demonstrated that suppression of microRNAs might
protect cardiomyocytes and neurons against oxygen–glucose deprivation and …

Overexpression of microRNA-378 attenuates ischemia-induced apoptosis by inhibiting caspase-3 expression in cardiac myocytes

J Fang, XW Song, J Tian, HY Chen, DF Li, JF Wang… - Apoptosis, 2012 - Springer
MicroRNAs (miRNAs) are a novel class of powerful, endogenous regulators of gene
expression. In an intact rat model of myocardial ischemia caused by coronary artery ligation …

Inhibition of microRNA-9-5p protects against cardiac remodeling following myocardial infarction in mice

Y Xiao, Y Zhang, Y Chen, J Li, Z Zhang, Y Sun… - Human gene …, 2019 - liebertpub.com
Follistatin-like 1 (Fstl1) protects cardiomyocytes from a broad spectrum of pathologic injuries
including myocardial infarction (MI). It is worthy of note that although cardiac Fstl1 is …