Voriconazole is a new triazole antifungal agent with potent, wide-spectrum activity. Its
pharmacokinetics and metabolism have been studied in mouse, rat, rabbit, dog, guinea pig …

Voriconazole is a broad spectrum, triazole antifungal drug now well into the final phases of
clinical trials in humans. During preclinical phases of development, it was found that when …

Voriconazole is the first available second-generation triazole with potent activity against a
broad spectrum of clinically significant fungal pathogens, including Aspergillus, Candida …

OBJECTIVE: To review the pharmacology, in vitro susceptibility, pharmacokinetics, clinical
efficacy, and adverse effects of voriconazole, a triazole antifungal agent. DATA SOURCES …

Voriconazole, a second-generation triazole frequently used for the prophylaxis and
treatment of invasive fungal infections, undergoes complex metabolism mainly involving …

The objective of this study was to investigate the safety, tolembility, and pharmacokinetics of
oral voriconazole in subjects at high risk of developing fungal infections. This was a …

Aims Voriconazole is a new triazole with broad‐spectrum antifungal activity against clinically
significant and emerging pathogens. These studies evaluated the pharmacokinetics and …

Aims Voriconazole is a potent new triazole with broad‐spectrum antifungal activity against
clinically significant and emerging pathogens. The present study evaluated the safety …

Clinical pharmacokinetics of voriconazole - ScienceDirect Skip to main contentSkip to article
Elsevier logo Journals & Books Search RegisterSign in View PDF Download full issue Search …

Aims Voriconazole is a new triazole antifungal agent with activity against a range of clinically
important and emerging pathogens. This study determined the effect of food on the …