[HTML][HTML] The MLL recombinome of acute leukemias in 2013
C Meyer, J Hofmann, T Burmeister, D Gröger, TS Park… - Leukemia, 2013 - nature.com
Chromosomal rearrangements of the human MLL (mixed lineage leukemia) gene are
associated with high-risk infant, pediatric, adult and therapy-induced acute leukemias. We …
associated with high-risk infant, pediatric, adult and therapy-induced acute leukemias. We …
New insights to the MLL recombinome of acute leukemias
C Meyer, E Kowarz, J Hofmann, A Renneville, J Zuna… - Leukemia, 2009 - nature.com
Chromosomal rearrangements of the human MLL gene are associated with high-risk
pediatric, adult and therapy-associated acute leukemias. These patients need to be …
pediatric, adult and therapy-associated acute leukemias. These patients need to be …
The MLL recombinome of acute leukemias
Chromosomal rearrangements of the human MLL gene are a hallmark for aggressive (high-
risk) pediatric, adult and therapy-associated acute leukemias. These patients need to be …
risk) pediatric, adult and therapy-associated acute leukemias. These patients need to be …
[HTML][HTML] The MLL recombinome of acute leukemias in 2017
Chromosomal rearrangements of the human MLL/KMT2A gene are associated with infant,
pediatric, adult and therapy-induced acute leukemias. Here we present the data obtained …
pediatric, adult and therapy-induced acute leukemias. Here we present the data obtained …
Diagnostic tool for the identification of MLL rearrangements including unknown partner genes
C Meyer, B Schneider, M Reichel… - Proceedings of the …, 2005 - National Acad Sciences
Approximately 50 different chromosomal translocations of the human MLL gene are
currently known and associated with high-risk acute leukemia. The large number of different …
currently known and associated with high-risk acute leukemia. The large number of different …
New insights into MLL gene rearranged acute leukemias using gene expression profiling: shared pathways, lineage commitment, and partner genes
A Kohlmann, C Schoch, M Dugas, S Schnittger… - Leukemia, 2005 - nature.com
Rearrangements of the MLL gene occur in both acute lymphoblastic and acute myeloid
leukemias (ALL, AML). This study addressed the global gene expression pattern of these …
leukemias (ALL, AML). This study addressed the global gene expression pattern of these …
MLL-rearranged leukemias: insights from gene expression profiling
SA Armstrong, TR Golub, SJ Korsmeyer - Seminars in hematology, 2003 - Elsevier
Gene expression analysis of human leukemias has provided insight into disease
classification and mechanisms of oncogenesis. Its success is particularly evident for acute …
classification and mechanisms of oncogenesis. Its success is particularly evident for acute …
Insights from clinical studies into the role of the MLL gene in infant and childhood leukemia
T Chowdhury, HJM Brady - Blood Cells, Molecules, and Diseases, 2008 - Elsevier
Translocations involving the Mixed Lineage Leukemia (MLL) gene at 11q23 are found in
both acute lymphoblastic leukemia (ALL) and acute myeloblastic leukemia (AML), but have …
both acute lymphoblastic leukemia (ALL) and acute myeloblastic leukemia (AML), but have …
Acute myeloid leukemia with MLL rearrangements: clinicobiological features, prognostic impact and value of flow cytometry in the detection of residual leukemic cells
L Munoz, JF Nomdedeu, N Villamor, R Guardia… - Leukemia, 2003 - nature.com
The MLL gene, located at 11q23 band, is frequently disrupted by different chromosomal
rearrangements that occur in a variety of hematological malignancies. MLL rearrangements …
rearrangements that occur in a variety of hematological malignancies. MLL rearrangements …
[HTML][HTML] MLL-rearranged leukemias—an update on science and clinical approaches
AC Winters, KM Bernt - Frontiers in pediatrics, 2017 - frontiersin.org
The mixed-lineage leukemia 1 (MLL1) gene (now renamed Lysine [K]-specific
MethylTransferase 2A or KMT2A) on chromosome 11q23 is disrupted in a unique group of …
MethylTransferase 2A or KMT2A) on chromosome 11q23 is disrupted in a unique group of …