HIV-1 regulation of latency in the monocyte-macrophage lineage and in CD4+ T lymphocytes
L Redel, V Le Douce, T Cherrier… - Journal of leukocyte …, 2010 - academic.oup.com
Review of molecular mechanisms of latency used by HIV-1 to establish viral reservoirs
within CD4 T cells and/or macrophages. The introduction in 1996 of the HAART raised …
within CD4 T cells and/or macrophages. The introduction in 1996 of the HAART raised …
[HTML][HTML] Eradication of HIV-1 from the macrophage reservoir: an uncertain goal?
Human immunodeficiency virus type 1 (HIV-1) establishes latency in resting memory CD4+
T cells and cells of myeloid lineage. In contrast to the T cells, cells of myeloid lineage are …
T cells and cells of myeloid lineage. In contrast to the T cells, cells of myeloid lineage are …
HIV replication and latency in monocytes and macrophages
RT Veenhuis, CM Abreu, EN Shirk, L Gama… - Seminars in …, 2021 - Elsevier
The relevance of monocyte and macrophage reservoirs in virally suppressed people with
HIV (vsPWH) has previously been debatable. Macrophages were assumed to have a …
HIV (vsPWH) has previously been debatable. Macrophages were assumed to have a …
[HTML][HTML] Molecular mechanisms of HIV-1 persistence in the monocyte-macrophage lineage
V Le Douce, G Herbein, O Rohr, C Schwartz - Retrovirology, 2010 - Springer
The introduction of the highly active antiretroviral therapy (HAART) has greatly improved
survival. However, these treatments fail to definitively cure the patients and unveil the …
survival. However, these treatments fail to definitively cure the patients and unveil the …
[HTML][HTML] HIV interactions with monocytes and dendritic cells: viral latency and reservoirs
CM Coleman, L Wu - Retrovirology, 2009 - Springer
HIV is a devastating human pathogen that causes serious immunological diseases in
humans around the world. The virus is able to remain latent in an infected host for many …
humans around the world. The virus is able to remain latent in an infected host for many …
[HTML][HTML] The role of macrophages in HIV-1 persistence and pathogenesis
Z Kruize, NA Kootstra - Frontiers in microbiology, 2019 - frontiersin.org
Current antiretroviral therapy (ART) effectively suppresses Human Immunodeficiency Virus
type 1 (HIV-1) in infected individuals. However, even long term ART does not eradicate HIV …
type 1 (HIV-1) in infected individuals. However, even long term ART does not eradicate HIV …
Latency in human immunodeficiency virus type 1 infection: no easy answers
For some viruses, long-term persistence in the host depends on the establishment of
latency, a reversibly nonproductive state of infection. The alphaherpesviruses provide a …
latency, a reversibly nonproductive state of infection. The alphaherpesviruses provide a …
Cellular reservoirs of HIV-1 and their role in viral persistence
A Alexaki, Y Liu, B Wigdahl - Current HIV research, 2008 - ingentaconnect.com
A major obstacle in human immunodeficiency virus type 1 (HIV-1) eradication is the ability of
the virus to remain latent in a subpopulation of the cells it infects. Latently infected cells can …
the virus to remain latent in a subpopulation of the cells it infects. Latently infected cells can …
HIV and cells of macrophage/dendritic lineage and other non-T cell reservoirs: new answers yield new questions
Defining how human immunodeficiency virus (HIV) interacts with macrophages, dendritic
cells (DC), and other non-T cell reservoirs remains a critical area of research despite …
cells (DC), and other non-T cell reservoirs remains a critical area of research despite …