Abstract Fine particulate matter (PM2. 5) is one of the most important components of
environmental pollutants and is associated with lung injury. Pyroptosis, a form of …

Abstract Particulate matter 2.5 (PM2. 5)‐induced pulmonary inflammation has become a
public concern in recent years. In which, the activation of the NLRP3/caspase‐1 pathway …

Acute lung injury and acute respiratory distress syndrome (ALI/ARDS) is characterized by
uncontrolled progressive lung inflammation. Macrophages serve a key role in the …

Growing evidences indicate that inflammation induced by PM2. 5 exposure has been
considered as a major driving force for the development of cardiovascular diseases …

Abstract Air particulate matter 2.5 (PM 2.5) has been demonstrated to exaggerate insulin
resistance in both human and animal studies. However, the exact molecular mechanisms …

Airborne fine particulate matter (PM 2.5) has been known capable of causing lung
inflammation and fibrosis, as a result of a series of chronic respiration diseases. Although …

Inspiration of a high concentration of oxygen, a therapy for acute lung injury (ALI), could
unexpectedly lead to reactive oxygen species (ROS) production and hyperoxia-induced …

Acute inflammation in response to both exogenous and endogenous danger signals can
lead to the assembly of cytoplasmic inflammasomes that stimulate the activation of caspase …

Objective Ozone has become a major air pollutant in recent years, which leading to a variety
of lung diseases. This study aimed to explore the mechanisms of pyroptosis and related …

Background Uncontrolled inflammation is a typical feature of sepsis-related lung injury. The
key event in the progression of lung injury is Caspase-1-dependent alveolar macrophage …