Quantitative measurement of pain sensation in patients with Parkinson disease

R Djaldetti, A Shifrin, Z Rogowski, E Sprecher… - Neurology, 2004 - AAN Enterprises
Background: Pain is common in patients with Parkinson disease (PD) and can precede the
diagnosis of the disease. Experimental studies and clinical evidence indicate involvement of …

Spontaneous pain, pain threshold, and pain tolerance in Parkinson's disease

S Zambito Marsala, M Tinazzi, R Vitaliani, S Recchia… - Journal of …, 2011 - Springer
The mechanisms underlying pain in Parkinson's disease (PD) are unclear. Although a few
studies have reported that PD patients may have low pain threshold and tolerance, none …

Neurophysiologic study of central pain in patients with Parkinson disease

P Schestatsky, H Kumru, J Valls-Sole, F Valldeoriola… - Neurology, 2007 - AAN Enterprises
Background: Patients with Parkinson disease (PD) may present with various types of pain. In
some instances, no cause can be identified and pain is considered a primary disorder …

Nociceptive brain activation in patients with neuropathic pain related to Parkinson's disease

C Brefel-Courbon, F Ory-Magne, C Thalamas… - Parkinsonism & Related …, 2013 - Elsevier
BACKGROUND: Patients suffering from Parkinson's disease (PD) frequently experience
painful sensations that may be due to central modification of nociception in PD. We …

Levodopa raises objective pain threshold in Parkinson's disease: a RIII reflex study

A Gerdelat-Mas, M Simonetta-Moreau… - Journal of Neurology …, 2007 - jnnp.bmj.com
Background: Patients suffering from Parkinson's disease (PD) describe painful sensations
that could be related to neuropathic pain. Experimental data have indicated the involvement …

Pain perception in Parkinson's disease: a systematic review and meta-analysis of experimental studies

T Thompson, K Gallop, CU Correll, AF Carvalho… - Ageing Research …, 2017 - Elsevier
While hyperalgesia (increased pain sensitivity) has been suggested to contribute to the
increased prevalence of clinical pain in Parkinson's disease (PD), experimental research is …

Chronic pain and pain processing in Parkinson's disease

PJ Blanchet, C Brefel-Courbon - Progress in Neuro-Psychopharmacology …, 2018 - Elsevier
Pain is experienced by the vast majority of patients living with Parkinson's disease. It is most
often of nociceptive origin, but may also be ascribed to neuropathic (radicular or central) or …

Sensory abnormalities and pain in Parkinson disease and its modulation by treatment of motor symptoms

RG Cury, R Galhardoni, ET Fonoff… - … journal of pain, 2016 - Wiley Online Library
Pain and sensory abnormalities are present in a large proportion of Parkinson disease (PD)
patients and have a significant negative impact in quality of life. It remains undetermined …

Pain as a nonmotor symptom of Parkinson disease: evidence from a case-control study

G Defazio, A Berardelli, G Fabbrini… - Archives of …, 2008 - jamanetwork.com
Objective To determine whether pain is more frequent among people with Parkinson
disease (PD) than among age-matched controls. Design Case-control study. Patients and …

The pathophysiological basis of sensory disturbances in Parkinson's disease

C Juri, MC Rodriguez-Oroz, JA Obeso - Journal of the neurological …, 2010 - Elsevier
The diagnosis of Parkinson's disease (PD) is still based on the recognition of the cardinal
motor features. However, it is now recognized that non-motor manifestations (NMM) may …