Sex, the aging immune system, and chronic disease

MRG Bupp - Cellular immunology, 2015 - Elsevier
The immune systems of men and women differ in significant ways, especially after puberty.
In particular, females are generally more prone to autoimmunity, but experience lower rates …

[HTML][HTML] The confluence of sex hormones and aging on immunity

MR Gubbels Bupp, T Potluri, AL Fink… - Frontiers in …, 2018 - frontiersin.org
The immune systems of post-pubescent males and females differ significantly with profound
consequences to health and disease. In many cases, sex-specific differences in the immune …

How sex and age affect immune responses, susceptibility to infections, and response to vaccination

C Giefing‐Kröll, P Berger, G Lepperdinger… - Aging cell, 2015 - Wiley Online Library
Do men die young and sick, or do women live long and healthy? By trying to explain the
sexual dimorphism in life expectancy, both biological and environmental aspects are …

[HTML][HTML] Sex, gender and immunosenescence: a key to understand the different lifespan between men and women?

C Caruso, G Accardi, C Virruso, G Candore - Immunity & Ageing, 2013 - Springer
Gender and sex are known to be associated with longevity. While males are usually
stronger, females live longer. In the Western world, the life expectancy of individual born …

The immune system and aging: a review

C Castelo-Branco, I Soveral - Gynecological Endocrinology, 2014 - Taylor & Francis
The concept of immunosenescence reflects age-related changes in immune responses,
both cellular and serological, affecting the process of generating specific responses to …

Immune senescence, epigenetics and autoimmunity

D Ray, R Yung - Clinical immunology, 2018 - Elsevier
Aging of the immune system in humans and animals is characterized by a decline in both
adaptive and innate immune responses. Paradoxically, aging is also associated with a state …

[HTML][HTML] The challenge by multiple environmental and biological factors induce inflammation in aging: their role in the promotion of chronic disease

MC Bachmann, S Bellalta, R Basoalto… - Frontiers in …, 2020 - frontiersin.org
The aging process is driven by multiple mechanisms that lead to changes in energy
production, oxidative stress, homeostatic dysregulation and eventually to loss of functionality …

[图书][B] Immunology and aging

T Makinodan - 2012 - books.google.com
In the classic sense, immunity is the ability of an organism to resist disease. On the one
hand, we must distinguish between age and disease; on the other hand, the interaction …

The immune system and its dysregulation with aging

L Müller, S Di Benedetto, G Pawelec - … and cell biology of ageing: Part II …, 2019 - Springer
Aging leads to numerous changes that affect all physiological systems of the body including
the immune system, causing greater susceptibility to infectious disease and contributing to …

Age-associated alterations in immune function and inflammation

ED Lewis, D Wu, SN Meydani - Progress in Neuro-Psychopharmacology …, 2022 - Elsevier
Immunosenescence is a term used to describe the age-related changes in the immune
system. Immunosenescence is associated with complex alterations and dysregulation of …