[HTML][HTML] Dynamic persistence of UPEC intracellular bacterial communities in a human bladder-chip model of urinary tract infection

K Sharma, N Dhar, VV Thacker, TM Simonet… - Elife, 2021 - elifesciences.org
Uropathogenic Escherichia coli (UPEC) proliferate within superficial bladder umbrella cells
to form intracellular bacterial communities (IBCs) during early stages of urinary tract …

Distinct Morphological Fates of Uropathogenic Escherichia coli Intracellular Bacterial Communities: Dependency on Urine Composition and pH

G Iosifidis, IG Duggin - Infection and Immunity, 2020 - Am Soc Microbiol
Uropathogenic Escherichia coli (UPEC) is the leading cause of urinary tract infections.
These bacteria undertake a multistage infection cycle involving invasion of and proliferation …

Population dynamics and niche distribution of uropathogenic Escherichia coli during acute and chronic urinary tract infection

DJ Schwartz, SL Chen, SJ Hultgren… - Infection and …, 2011 - Am Soc Microbiol
Urinary tract infections (UTIs) have complex dynamics, with uropathogenic Escherichia coli
(UPEC), the major causative agent, capable of colonization from the urethra to the kidneys in …

Urothelial Cultures Support Intracellular Bacterial Community Formation by Uropathogenic Escherichia coli

RE Berry, DJ Klumpp, AJ Schaeffer - Infection and immunity, 2009 - Am Soc Microbiol
Uropathogenic Escherichia coli (UPEC) causes most community-acquired and nosocomial
urinary tract infections (UTI). In a mouse model of UTI, UPEC invades superficial bladder …

[HTML][HTML] Detection of intracellular bacterial communities in human urinary tract infection

DA Rosen, TM Hooton, WE Stamm, PA Humphrey… - PLoS …, 2007 - journals.plos.org
Background Urinary tract infections (UTIs) are one of the most common bacterial infections
and are predominantly caused by uropathogenic Escherichia coli (UPEC). While UTIs are …

Escherichia coli from Urine of Female Patients with Urinary Tract Infections Is Competent for Intracellular Bacterial Community Formation

CK Garofalo, TM Hooton, SM Martin… - Infection and …, 2007 - Am Soc Microbiol
Nearly 50% of women experience at least one urinary tract infection (UTI) in their lifetime.
Studies with mice have revealed that uropathogenic Escherichia coli (UPEC) isolates invade …

Differentiation and developmental pathways of uropathogenic Escherichia coli in urinary tract pathogenesis

SS Justice, C Hung, JA Theriot… - Proceedings of the …, 2004 - National Acad Sciences
Uropathogenic Escherichia coli (UPEC) are capable of forming complex intracellular
bacterial communities (IBC) within the superficial umbrella cells of the bladders of C3H and …

Metabolic requirements of Escherichia coli in intracellular bacterial communities during urinary tract infection pathogenesis

MS Conover, M Hadjifrangiskou, JJ Palermo… - MBio, 2016 - Am Soc Microbiol
Uropathogenic Escherichia coli (UPEC) is the primary etiological agent of over 85% of
community-acquired urinary tract infections (UTIs). Mouse models of infection have shown …

Actin‐gated intracellular growth and resurgence of uropathogenic Escherichia coli

DS Eto, JL Sundsbak, MA Mulvey - Cellular microbiology, 2006 - Wiley Online Library
Strains of uropathogenic Escherichia coli (UPEC) can invade terminally differentiated
superficial bladder epithelial cells and subsequently multiply, forming large biofilm‐like …

[HTML][HTML] Host subversion by formation of intracellular bacterial communities in the urinary tract

GG Anderson, SM Martin, SJ Hultgren - Microbes and infection, 2004 - Elsevier
Urinary tract infections pose a serious health threat with respect to antibiotic resistance and
high recurrence rates. While the host robustly responds to bacterial infiltration into the …