Integron involvement in environmental spread of antibiotic resistance

T Stalder, O Barraud, M Casellas, C Dagot… - Frontiers in …, 2012 - frontiersin.org
The spread of antibiotic-resistant bacteria is a growing problem and a public health issue. In
recent decades, various genetic mechanisms involved in the spread of resistance genes …

Integrons: past, present, and future

MR Gillings - Microbiology and molecular biology reviews, 2014 - Am Soc Microbiol
Integrons are versatile gene acquisition systems commonly found in bacterial genomes.
They are ancient elements that are a hot spot for genomic complexity, generating phenotypic …

Integrons in the development of antimicrobial resistance: critical review and perspectives

BA Bhat, RA Mir, H Qadri, R Dhiman… - Frontiers in …, 2023 - frontiersin.org
Antibiotic resistance development and pathogen cross-dissemination are both considered
essential risks to human health on a worldwide scale. Antimicrobial resistance genes …

Dissemination of antibiotic resistance genes (ARGs) via integrons in Escherichia coli: a risk to human health

S Zhang, M Abbas, MU Rehman, Y Huang, R Zhou… - Environmental …, 2020 - Elsevier
With the induction of various emerging environmental contaminants such as antibiotic
resistance genes (ARGs), environment is considered as a key indicator for the spread of …

Class 1 integrons, gene cassettes, mobility, and epidemiology

AC Fluit, FJ Schmitz - European Journal of Clinical Microbiology and …, 1999 - Springer
Integrons are genetic elements that, although unable to move themselves, contain gene
cassettes that can be mobilized to other integrons or to secondary sites in the bacterial …

Quantitative and qualitative impact of hospital effluent on dissemination of the integron pool

T Stalder, O Barraud, T Jové, M Casellas… - The ISME …, 2014 - academic.oup.com
There is increasing evidence that human activity, and especially the resulting effluent, has a
major role in the dissemination of bacterial antibiotic-resistance determinants in the …

Widespread dissemination of class 1 integron components in soils and related ecosystems as revealed by cultivation-independent analysis

S Jechalke, S Schreiter, B Wolters, S Dealtry… - Frontiers in …, 2014 - frontiersin.org
Class 1 integrons contribute to the emerging problem of antibiotic resistance in human
medicine by acquisition, exchange, and expression of resistance genes embedded within …

Quantification of class 1 integron abundance in natural environments using real-time quantitative PCR

SA Hardwick, HW Stokes, S Findlay… - FEMS microbiology …, 2008 - academic.oup.com
Integrons are bacterial genetic elements capable of capturing and expressing potentially
adaptive genetic material. Class 1 integrons constitute the most intensely studied group of …

The natural history of integrons

TM Ghaly, MR Gillings, A Penesyan, Q Qi, V Rajabal… - Microorganisms, 2021 - mdpi.com
Integrons were first identified because of their central role in assembling and disseminating
antibiotic resistance genes in commensal and pathogenic bacteria. However, these clinically …

[HTML][HTML] Integron and its role in antimicrobial resistance: A literature review on some bacterial pathogens

P Sabbagh, M Rajabnia, A Maali… - Iranian journal of …, 2021 - ncbi.nlm.nih.gov
In recent years, different acquired resistance mechanisms, including transposons,
bacteriophages, plasmids, and integrons have been identified as involved in the spread of …