Therapeutic hypothermia (TH) is now a standard treatment for infants with moderate-to-
severe neonatal encephalopathy (NE), and improves brain damage on neuroimaging and …

Infants with moderate to severe neonatal encephalopathy (NE) benefit significantly from
therapeutic hypothermia, with reduced risk of death or disability. However, the need for …

Although neonatal hypoxic-ischemic encephalopathy is a common cause of childhood
developmental disability, its timing, duration, and outcomes are poorly defined. Biomarkers …

Neonatal encephalopathy (NE) continues to have a major impact on newborn survival and
neurodevelopmental outcomes worldwide. In high-income settings, therapeutic hypothermia …

There is increasing evidence that infants with mild neonatal encephalopathy (NE) have
significant risks of mortality, brain injury and adverse neurodevelopmental outcomes. In the …

Background Therapeutic hypothermia (TH) is routinely provided to those with moderate or
severe neonatal encephalopathy (NE). Subtle differences exist in the standardized exams …

Introduction: Adverse outcomes have been reported in infants with mild neonatal
encephalopathy (NE). Increasing clinical experience with the application of therapeutic …

Neonatal encephalopathy after perinatal hypoxic-ischemic insult is a major contributor to
global child mortality and morbidity. Brain injury in term infants in response to hypoxic …

In randomized trials, therapeutic hypothermia (TH) is associated with reduced prevalence of
the composite outcome mortality or neurodevelopmental morbidity in infants with neonatal …

Objective Identifying term infants presenting with early mild neonatal encephalopathy (NE)
as candidates for therapeutic hypothermia (TH) remains unclear. Study objectives were to …