Longitudinal biomarkers in amyotrophic lateral sclerosis
F Huang, Y Zhu, J Hsiao‐Nakamoto… - Annals of clinical …, 2020 - Wiley Online Library
Objective To investigate neurodegenerative and inflammatory biomarkers in people with
amyotrophic lateral sclerosis (PALS), evaluate their predictive value for ALS progression …
amyotrophic lateral sclerosis (PALS), evaluate their predictive value for ALS progression …
Humoral factors in ALS patients during disease progression
Background Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting
upper and lower motor neurons in the CNS and leading to paralysis and death. There are …
upper and lower motor neurons in the CNS and leading to paralysis and death. There are …
Inflammatory profiles relate to survival in subtypes of amyotrophic lateral sclerosis
MN Olesen, A Wuolikainen, AC Nilsson… - Neurology …, 2020 - AAN Enterprises
Objective To investigate inflammatory cytokines in patients with motor neuron disease
(MND) evaluating the putative contribution of amyotrophic lateral sclerosis (ALS)-causing …
(MND) evaluating the putative contribution of amyotrophic lateral sclerosis (ALS)-causing …
Serum biomarkers of neuroinflammation and blood-brain barrier leakage in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is an incurable and rapidly progressive neurological
disorder. Biomarkers are critical to understanding disease causation, monitoring disease …
disorder. Biomarkers are critical to understanding disease causation, monitoring disease …
Amyotrophic lateral sclerosis multiprotein biomarkers in peripheral blood mononuclear cells
Background Amyotrophic lateral sclerosis (ALS) is a fatal progressive motor neuron disease,
for which there are still no diagnostic/prognostic test and therapy. Specific molecular …
for which there are still no diagnostic/prognostic test and therapy. Specific molecular …
Serum C-reactive protein as a prognostic biomarker in amyotrophic lateral sclerosis
Importance Various factors have been proposed as possible candidates associated with the
prognosis of amyotrophic lateral sclerosis (ALS); however, there is still no consensus on …
prognosis of amyotrophic lateral sclerosis (ALS); however, there is still no consensus on …
Phosphorylated neurofilament heavy chain: A biomarker of survival for C9ORF72‐associated amyotrophic lateral sclerosis
TF Gendron, LM Daughrity, MG Heckman… - Annals of …, 2017 - Wiley Online Library
As potential treatments for C9ORF72‐associated amyotrophic lateral sclerosis (c9ALS)
approach clinical trials, the identification of prognostic biomarkers for c9ALS becomes a …
approach clinical trials, the identification of prognostic biomarkers for c9ALS becomes a …
Plasma profiling reveals three proteins associated to amyotrophic lateral sclerosis
A Häggmark, M Mikus, A Mohsenchian… - Annals of clinical …, 2014 - Wiley Online Library
Objective Amyotrophic lateral sclerosis (ALS) is the most common adult motor neuron
disease leading to muscular paralysis and death within 3–5 years from onset. Currently …
disease leading to muscular paralysis and death within 3–5 years from onset. Currently …
Elevated acute phase proteins reflect peripheral inflammation and disease severity in patients with amyotrophic lateral sclerosis
DR Beers, W Zhao, DW Neal, JR Thonhoff… - Scientific reports, 2020 - nature.com
Amyotrophic lateral sclerosis (ALS) is a multifactorial, multisystem pro-inflammatory
neuromuscular disorder compromising muscle function resulting in death …
neuromuscular disorder compromising muscle function resulting in death …
Phase 2B randomized controlled trial of NP001 in amyotrophic lateral sclerosis: pre‐specified and post hoc analyses
RG Miller, R Zhang, PM Bracci, A Azhir… - Muscle & …, 2022 - Wiley Online Library
Introduction/Aims ALS is a heterogeneous disease that may be complicated or in part driven
by inflammation. NP001, a regulator of macrophage activation, was associated with slowing …
by inflammation. NP001, a regulator of macrophage activation, was associated with slowing …