Combining the potential of 3D printed buccal films and nanostructured lipid carriers for personalised cannabidiol delivery

S Abdella, S Kim, F Afinjuomo, Y Song, R Upton… - Drug Delivery and …, 2024 - Springer
Cannabidiol (CBD) has been recognized for its numerous therapeutic benefits, such as
neuroprotection, anti-inflammatory effects, and cardioprotection. However, CBD has some …

Enhancing transmucosal delivery of CBD through nanoemulsion: in vitro and in vivo studies

R Provenzano, C De Caro, A Vitiello, L Izzo… - Drug Delivery and …, 2024 - Springer
Cannabidiol (CBD) has gained significant attention as a complementary and alternative
medicine due to its promising therapeutic properties. However, CBD faces obstacles when …

Poly(ethylene glycol)-b-poly(epsilon-caprolactone) nanoparticles as a platform for the improved oral delivery of cannabidiol

I Shreiber-Livne, L Sulimani, A Shapira… - Drug Delivery and …, 2023 - Springer
Abstract Cannabidiol (CBD), a non-psychoactive constituent of Cannabis, has proven
neuroprotective, anti-inflammatory and antioxidant properties though his therapeutic use …

Formulation and quality consideration of cannabidiol printed forms produced by fused-deposition modeling

O Jennotte, N Koch, A Lechanteur, B Evrard - Journal of Drug Delivery …, 2023 - Elsevier
Cannabidiol (CBD) is a promising non-psychoactive cannabinoid that shows several clinical
outcomes. Commercially, this molecule is used in Epidiolex®(Greenwich Biosciences, Inc) …

Mucoadhesive nanostructured lipid carriers as a cannabidiol nasal delivery system for the treatment of neuropathic pain

AP Matarazzo, LMS Elisei, FC Carvalho… - European Journal of …, 2021 - Elsevier
The therapeutic potential of cannabidiol (CBD) has been explored to treat several
pathologies, including those in which pain is prevalent. However, the oral bioavailability of …

3D DLP-printed cannabinoid microneedles patch and its pharmacokinetic evaluation in rats

A Bagde, K Mosley-Kellum, S Spencer… - Journal of Pharmacy …, 2024 - academic.oup.com
Objective The objective of the present study was to enhance the bioavailability of
cannabidiol (CBD) using 3D Digital Light Processing (DLP)-printed microneedle (MN) …

Strategies to Improve Cannabidiol Bioavailability and Drug Delivery

SE O'Sullivan, SS Jensen, AR Kolli, GN Nikolajsen… - Pharmaceuticals, 2024 - mdpi.com
The poor physicochemical properties of cannabidiol (CBD) hamper its clinical development.
The aim of this review was to examine the literature to identify novel oral products and …

Current trends on cannabidiol delivery systems: where are we and where are we going?

IM de Medeiros Ramalho… - Expert opinion on …, 2021 - pubmed.ncbi.nlm.nih.gov
Introduction Cannabidiol (CBD), a phytocannabinoid from Cannabis sativa, has several
therapeutic properties. However, its high lipophilicity, metabolization, and instability impair …

Current trends on cannabidiol delivery systems: where are we and where are we going?

ÍMM Ramalho, DT Pereira, GBL Galvão… - Expert Opinion on …, 2021 - Taylor & Francis
Introduction Cannabidiol (CBD), a phytocannabinoid from Cannabis sativa, has several
therapeutic properties. However, its high lipophilicity, metabolization, and instability impair …

Cannabidiol-loaded nanostructured lipid carriers (NLCs) for dermal delivery: enhancement of photostability, cell viability, and anti-inflammatory activity

B Morakul, VB Junyaprasert, K Sakchaisri… - Pharmaceutics, 2023 - mdpi.com
The aim of this study was to encapsulate cannabidiol (CBD) extract in nanostructured lipid
carriers (NLCs) to improve the chemical stability and anti-inflammatory activity of CBD for …