[HTML][HTML] Bronchoscopic instillation of amphotericin B is a safe and effective measure to treat pulmonary mycosis

L Yang, C Yang, N Wan, W Xie, Y Tian… - Frontiers in …, 2023 - frontiersin.org
Background and objectives: In recent years, there has been a significant increase in the
prevalence of pulmonary mycosis disease, and its mortality has increased. There are very …

Treatment of invasive pulmonary aspergillosis in neutropenic patients by additional bronchoscopic amphotericin B instillation

J Winkler, U Müller, P Nenoff, HJ Seyfarth, M Vogtmann… - Respiration, 2007 - karger.com
Background: Invasive pulmonary aspergillosis (IPA) remains a life-threatening condition
despite systemic antifungal therapy. Objectives: This retrospective analysis investigated …

[HTML][HTML] Pulmonary mycoses treated by topical amphotericin B

FHO AL-Khikani - Biomedical and Biotechnology Research …, 2020 - journals.lww.com
Since its discovery, amphotericin B (AmB) became a key management because it is the most
common antifungal drug with activity to disrupt the fungal cell wall. Furthermore, it is the first …

[HTML][HTML] Successful treatment of invasive tracheobronchial pulmonary aspergillosis with venovenous extracorporeal membrane oxygenation and combined systemic …

S Sato, W Kamata, K Fukaguchi, S Tsunoda… - Journal of Medical Case …, 2022 - Springer
Abstract Background Invasive pulmonary Aspergillus and invasive bronchial aspergillosis is
a life-threatening opportunistic fungal infection that predominantly affects …

[HTML][HTML] Application and evaluation of topical amphotericin B for the treatment of respiratory fungal infections

N Cui, J Zhao - BMC Infectious Diseases, 2024 - Springer
Background In recent years, the prevalence of respiratory fungal diseases has increased.
Polyene antifungal drugs play a pivotal role in the treatment of these conditions, with …

An open‐label non‐inferiority randomised control trial comparing nebulised amphotericin B with oral itraconazole in patients with pulmonary aspergilloma

A Ray, J Manikanta, K Singh, P Gabra, S Vyas… - Mycoses, 2021 - Wiley Online Library
Background Pulmonary aspergilloma (PA) is a common complication seen in patients with
pulmonary tuberculosis sequelae. Antifungal therapy, including oral azoles, is commonly …

[HTML][HTML] Could the Lung Be a Gateway for Amphotericin B to Attack the Army of Fungi?

BF de Carvalho Patricio, JO da Silva Lopes Pereira… - Pharmaceutics, 2022 - mdpi.com
Fungal diseases are a significant cause of morbidity and mortality worldwide, primarily
affecting immunocompromised patients. Aspergillus, Pneumocystis, and Cryptococcus are …

Percutaneous treatment with amphotericin B of mycotic lung lesions from invasive aspergillosis: results in 10 immunocompromised patients

A Veltri, GC Anselmetti, G Bartoli, MC Martina… - European …, 2000 - Springer
The aim of this study was to evaluate the efficacy of percutaneous treatment of pulmonary
lesions from invasive aspergillosis in immunocompromised patients. From 1992 to 1998, ten …

Efficacy of combination antifungal therapy with intraperitoneally administered micafungin and aerosolized liposomal amphotericin B against murine invasive …

T Takazono, K Izumikawa, T Mihara… - Antimicrobial agents …, 2009 - Am Soc Microbiol
Targeted intrapulmonary delivery of drugs may reduce systemic toxicity and improve
treatment efficacy. In the current study, we evaluated the effects of a combination treatment …

Combination therapy with micafungin and amphotericin B for invasive pulmonary aspergillosis in an immunocompromised mouse model

Y Nagasaki, Y Eriguchi, Y Uchida… - Journal of …, 2009 - academic.oup.com
Objectives Antifungal monotherapy with polyenes, azoles or echinocandins is not always
effective for invasive pulmonary aspergillosis (IPA). The main purpose of this study was to …