γ-Aminobutyric acid (GABA) signalling in plants

SA Ramesh, SD Tyerman, M Gilliham, B Xu - Cellular and Molecular Life …, 2017 - Springer
The role of γ-aminobutyric acid (GABA) as a signal in animals has been documented for
over 60 years. In contrast, evidence that GABA is a signal in plants has only emerged in the …

GABA signalling modulates plant growth by directly regulating the activity of plant-specific anion transporters

SA Ramesh, SD Tyerman, B Xu, J Bose, S Kaur… - Nature …, 2015 - nature.com
The non-protein amino acid, gamma-aminobutyric acid (GABA) rapidly accumulates in plant
tissues in response to biotic and abiotic stress, and regulates plant growth. Until now it was …

Linking metabolism to membrane signaling: the GABA–malate connection

M Gilliham, SD Tyerman - Trends in plant science, 2016 - cell.com
γ-Aminobutyric acid (GABA) concentration increases rapidly in tissues when plants
encounter abiotic or biotic stress, and GABA manipulation affects growth. This, coupled to …

The emerging role of GABA as a transport regulator and physiological signal

B Xu, N Sai, M Gilliham - Plant Physiology, 2021 - academic.oup.com
While the proposal that γ-aminobutyric acid (GABA) acts a signal in plants is decades old, a
signaling mode of action for plant GABA has been unveiled only relatively recently. Here, we …

GABA signaling: a conserved and ubiquitous mechanism

N Bouché, B Lacombe, H Fromm - Trends in cell biology, 2003 - cell.com
In plants, research on γ-aminobutyric acid (GABA) has focused on its role as a metabolite,
mainly in the context of responses to biotic and abiotic stresses. By contrast, studies of GABA …

Aluminum-activated malate transporters can facilitate GABA transport

SA Ramesh, M Kamran, W Sullivan, L Chirkova… - The Plant …, 2018 - academic.oup.com
Plant aluminum-activated malate transporters (ALMTs) are currently classified as anion
channels; they are also known to be regulated by diverse signals, leading to a range of …

Closing the loop on the GABA shunt in plants: are GABA metabolism and signaling entwined?

S Michaeli, H Fromm - Frontiers in plant science, 2015 - frontiersin.org
γ-Aminobutyric acid (GABA) is a non-proteinogenic amino acid that is found in uni-and multi-
cellular organisms and is involved in many aspects of plant life cycle. GABA metabolism …

Emerging roles of γ aminobutyric acid (GABA) gated channels in plant stress tolerance

M Kaspal, MH Kanapaddalagamage, SA Ramesh - Plants, 2021 - mdpi.com
The signaling role for γ-Aminobutyric acid (GABA) has been documented in animals for over
seven decades. However, a signaling role for GABA in plants is just beginning to emerge …

The versatile GABA in plants

L Li, N Dou, H Zhang, C Wu - Plant signaling & behavior, 2021 - Taylor & Francis
Gamma-aminobutyric acid (GABA) is a ubiquitous four-carbon, non-protein amino acid.
GABA has been widely studied in animal central nervous systems, where it acts as an …

GABA signaling in plants: targeting the missing pieces of the puzzle

H Fromm - Journal of experimental botany, 2020 - academic.oup.com
The adaptation of plants to unstable environments relies on their ability to sense their
surroundings and to generate and transmit corresponding signals to different parts of the …