It is known that shorter stature is associated with sensorineural hearing loss; and that
cochlear development is associated with activity of IGF 1, as are many important aspects of …

Insulin-like growth factors (IGFs) have a pivotal role during nervous system development
and in its functional maintenance. IGF-I and its high affinity receptor (IGF1R) are expressed …

In order to test the Thrifty Phenotype Hypothesis on hearing, data from two cross-sectional
studies on hearing were re-evaluated. The data sets comprised 500 18-year-old conscripts …

Insulin-like growth factor 1 (IGF-1) modulates inner ear cell proliferation, differentiation and
survival in culture. Its function in human hearing was first evidenced by a report of a boy with …

Abstract Insulin-like Growth Factor 1 (IGF-1) is associated with cardiovascular disease, itself
a risk factor for hearing impairment, and, in animal studies, molecular evidence suggests a …

Objective Although insulin-like growth factor 1 (IGF-1) has been shown to be important for
inner-ear development in animal models, little is known about the otologic and audiologic …

Insulin-like growth factor 1: role in the auditory system an... : Current Opinion in Otolaryngology
& Head and Neck Surgery Insulin-like growth factor 1: role in the auditory system and …

It has been reported that mutations in the gene encoding human insulin‐like growth factor‐I
(IGF‐I) cause syndromic hearing loss. To study the precise role of IGF‐I in auditory function …

Insulin-like growth factor 1 (IGF-1) is a peptide hormone belonging to the insulin family of
proteins. Almost all of the biological effects of IGF-1 are mediated through binding to its high …

Aging is associated with impairment of sensorial functions and with the onset of
neurodegenerative diseases. As pari passu circulating insulin-like growth factor 1 (IGF-1) …