[HTML][HTML] Molecular basis and clinical significance of genetic aberrations in B-cell precursor acute lymphoblastic leukemia
F Ghazavi, T Lammens, N Van Roy, B Poppe… - Experimental …, 2015 - Elsevier
Highlights•B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is currently treated by
risk-adapted intensive chemotherapy•Genome-wide genomic analyses have uncovered the …
risk-adapted intensive chemotherapy•Genome-wide genomic analyses have uncovered the …
[HTML][HTML] New biological and genetic classification and therapeutically relevant categories in childhood B-cell precursor acute lymphoblastic leukemia
J Starý, J Zuna, M Zaliova - F1000Research, 2018 - ncbi.nlm.nih.gov
Traditionally, genetic abnormalities detected by conventional karyotyping, fluorescence in
situ hybridization, and polymerase chain reaction divided childhood B-cell precursor acute …
situ hybridization, and polymerase chain reaction divided childhood B-cell precursor acute …
Transcriptional landscape of B cell precursor acute lymphoblastic leukemia based on an international study of 1,223 cases
Most B cell precursor acute lymphoblastic leukemia (BCP ALL) can be classified into known
major genetic subtypes, while a substantial proportion of BCP ALL remains poorly …
major genetic subtypes, while a substantial proportion of BCP ALL remains poorly …
[HTML][HTML] RAS pathway mutations as a predictive biomarker for treatment adaptation in pediatric B-cell precursor acute lymphoblastic leukemia
IS Jerchel, AQ Hoogkamer, IM Ariës, EMP Steeghs… - Leukemia, 2018 - nature.com
RAS pathway mutations have been linked to relapse and chemotherapy resistance in
pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL). However …
pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL). However …
Genomic profiling of B-progenitor acute lymphoblastic leukemia
CG Mullighan - Best practice & research Clinical haematology, 2011 - Elsevier
Childhood acute lymphoblastic leukemia (ALL) is comprised of multiple subtypes defined by
recurring chromosomal alterations that are important events in leukemogenesis and are …
recurring chromosomal alterations that are important events in leukemogenesis and are …
[HTML][HTML] Emerging molecular subtypes and therapeutic targets in B-cell precursor acute lymphoblastic leukemia
B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is characterized by genetic
alterations with high heterogeneity. Precise subtypes with distinct genomic and/or gene …
alterations with high heterogeneity. Precise subtypes with distinct genomic and/or gene …
Landscape of driver mutations and their clinical impacts in pediatric B-cell precursor acute lymphoblastic leukemia
H Ueno, K Yoshida, Y Shiozawa, Y Nannya… - Blood …, 2020 - ashpublications.org
Recent genetic studies using high-throughput sequencing have disclosed genetic
alterations in B-cell precursor acute lymphoblastic leukemia (B-ALL). However, their effects …
alterations in B-cell precursor acute lymphoblastic leukemia (B-ALL). However, their effects …
[HTML][HTML] Adult acute lymphoblastic leukemia: a genetic overview and application to clinical practice
S Jacobson - Number 6/December 2016, 2016 - cjon.ons.org
Background: Cytogenetic and molecular features of diseases, such as B-cell precursor acute
lymphoblastic leukemia (BCP-ALL), are increasingly used for diagnostic, prognostic, and …
lymphoblastic leukemia (BCP-ALL), are increasingly used for diagnostic, prognostic, and …
Targeted locus amplification & next generation sequencing for the detection of recurrent and novel gene fusions for improved treatment decisions in pediatric acute …
RP Kuiper, SV van Reijmersdal, M Simonis, J Yu… - 2015 - ashpublications.org
Current risk assessments for treatment of children with B-cell precursor acute lymphoblastic
leukemia (BCP-ALL) are based on several clinical and biological criteria, including genomic …
leukemia (BCP-ALL) are based on several clinical and biological criteria, including genomic …
Advances in the molecular pathobiology of B-lymphoblastic leukemia
Y Zhou, MJ You, KH Young, P Lin, G Lu, LJ Medeiros… - Human pathology, 2012 - Elsevier
B-lymphoblastic leukemia/lymphoma, also known as B-acute lymphoblastic leukemia, is
derived from B-cell progenitors. B-acute lymphoblastic leukemia occurs predominantly in …
derived from B-cell progenitors. B-acute lymphoblastic leukemia occurs predominantly in …