[HTML][HTML] Intestinal barrier breakdown and mucosal microbiota disturbance in neuromyelitis optical spectrum disorders

C Cui, S Tan, L Tao, J Gong, Y Chang, Y Wang… - Frontiers in …, 2020 - frontiersin.org
Background and Purpose The mechanism underlying the pathology of neuromyelitis optica
spectrum disorders (NMOSD) remains unclear even though antibodies to the water channel …

Potential role of the gut microbiota in neuromyelitis optica spectrum disorder: Implication for intervention

C Cui, Y Ruan, W Qiu - Journal of Clinical Neuroscience, 2020 - Elsevier
The gut microbiota plays an important role in the occurrence and development of
neuroimmunological diseases. Neuromyelitis optica spectrum disorder (NMOSD) is an …

Dysbiosis of gut microbiota in patients with neuromyelitis optica spectrum disorders: a cross sectional study

Z Shi, Y Qiu, J Wang, Y Fang, Y Zhang, H Chen… - Journal of …, 2020 - Elsevier
Background Accumulating evidence points to an association of alternations in the gut
microbiota with health and disease, including the development of neurological diseases …

Characteristic of gut microbiota in southeastern Chinese patients with neuromyelitis optica spectrum disorders

J Zhang, YF Xu, L Wu, HF Li, ZY Wu - Multiple Sclerosis and Related …, 2020 - Elsevier
Background Emerging evidence indicated that gut microbiota might play an essential role in
the pathogenesis of neuromyelitis optica spectrum disorders (NMOSD). The results are …

The Role of Gut Microbiota in Neuromyelitis Optica Spectrum Disorder

SQ Yao, X Yang, LP Cen, S Tan - International Journal of Molecular …, 2024 - mdpi.com
Neuromyelitis optica spectrum disorder (NMOSD) is a rare, disabling inflammatory disease
of the central nervous system (CNS). Aquaporin-4 (AQP4)-specific T cells play a key role in …

Lack of short-chain fatty acids and overgrowth of opportunistic pathogens define dysbiosis of neuromyelitis optica spectrum disorders: a Chinese pilot study

J Gong, W Qiu, Q Zeng, X Liu, X Sun… - Multiple Sclerosis …, 2019 - journals.sagepub.com
Background: Intestinal microbiota is an important environmental factor in the initiation and
progression of autoimmune diseases. However, investigations on the gut microbiome in …

Clostridium bolteae is elevated in neuromyelitis optica spectrum disorder in India and shares sequence similarity with AQP4

L Pandit, LM Cox, C Malli, A D'Cunha… - Neurology …, 2020 - AAN Enterprises
Objective To understand the role of gut microbiome in influencing the pathogenesis of
neuromyelitis optica spectrum disorders (NMOSDs) among patients of south Indian origin …

Gut microbiota dysbiosis associated with different types of demyelinating optic neuritis in patients

Y Liu, H Fan, Y Shao, J Zhang, Z Zuo, J Wang… - Multiple Sclerosis and …, 2023 - Elsevier
Background Demyelinating optic neuritis (DON) causes rapid vision loss in young and
middle-aged people. The limited efficacy of treatment and the toxic side effects of drugs …

[HTML][HTML] Alterations in the brain structure and functional connectivity in aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder

J Yan, Y Wang, H Miao, WR Kwapong, Y Lu… - Frontiers in …, 2020 - frontiersin.org
Purpose To investigate the mechanisms underlying the gray matter volume (GMV) and
functional connectivity (FC) changes in aquaporin-4 antibody-positive neuromyelitis optica …

[HTML][HTML] GV‐971 attenuates the progression of neuromyelitis optica in murine models and reverses alterations in gut microbiota and associated peripheral …

X Yang, Z Zhangyi, A Yu, Q Zhou, A Xia… - CNS Neuroscience & …, 2024 - ncbi.nlm.nih.gov
Aims Growing evidence suggests that an imbalanced gut microbiota composition plays a
crucial role in the development of neuromyelitis optica spectrum disorders (NMOSD), an …