Pathogenesis and treatment of the adult respiratory distress syndrome

WJ Fulkerson, N MacIntyre, J Stamler… - Archives of internal …, 1996 - jamanetwork.com
The adult respiratory distress syndrome is an acute clinical illness characterized by
noncardiogenic pulmonary edema and refractory hypoxemia. Injury to the alveolar-capillary …

Inhaled nitric oxide in the adult respiratory distress syndrome and other lung diseases.

WM Zapol, WE Hurford - New Horizons (Baltimore, Md.), 1993 - europepmc.org
In 1987, nitric oxide was reported to be an endothelium-dependent relaxing factor. When
inhaled as a gas at low levels, nitric oxide selectively dilates the pulmonary circulation …

Inhaled nitric oxide for the adult respiratory distress syndrome

R Rossaint, KJ Falke, F Lopez, K Slama… - … England Journal of …, 1993 - Mass Medical Soc
Background The adult respiratory distress syndrome is characterized by pulmonary
hypertension and right-to-left shunting of venous blood. We investigated whether inhaling …

Inhaled nitric oxide in acute lung disease.

WG Cioffi Jr, H Ogura - New Horizons (Baltimore, Md.), 1995 - europepmc.org
The recognition that inhaled nitric oxide (NO.) selectively vasodilates the pulmonary
vasculature and the fact that pulmonary artery hypertension appears to play a pivotal and …

Effect of inhaled nitric oxide on right ventricular function in adult respiratory distress syndrome.

L Fierobe, F Brunet, JF Dhainaut, M Monchi… - American journal of …, 1995 - atsjournals.org
To determine whether inhaled nitric oxide (NO) affects pulmonary circulation, thereby
improving right ventricular (RV) function in adult respiratory distress syndrome (ARDS), we …

Prolonged inhalation of low concentrations of nitric oxide in patients with severe adult respiratory distress syndrome. Effects on pulmonary hemodynamics and …

LM Bigatello, WE Hurford, RM Kacmarek… - …, 1994 - europepmc.org
Background Nitric oxide (NO) inhalation selectively decreases pulmonary artery
hypertension and improves arterial oxygenation in patients with the adult respiratory distress …

Time‐course and dose‐response of nitric oxide inhalation for systemic oxygenation and pulmonary hypertension in patients with adult respiratory distress syndrome

H Gerlach, R Rossaint, D Pappert… - European journal of …, 1993 - Wiley Online Library
Inhalation of nitric oxide (NO), an endoge‐neous vasodilator, was recently described to
reduce pulmonary vascular resistance, and to improve arterial oxygenation by selective …

[HTML][HTML] Prevention and therapy of the adult respiratory distress syndrome

B Temmesfeld-Wollbrück, D Walmrath, F Grimminger… - Lung, 1995 - Springer
The complex pathophysiology of adult respiratory distress syndrome (ARDS) makes
preventive and therapeutic concepts difficult. Ample experimental evidence indicates that …

Life-threatening effects of discontinuing inhaled nitric oxide in severe respiratory failure.

A Lavoie, JB Hall, DM Olson… - American journal of …, 1996 - atsjournals.org
We present the effects of abrupt discontinuation of inhaled nitric oxide (NO) in four patients
with severe hypoxemic respiratory failure. These patients ranged from 9 mo to 65 yr of age …

Adult respiratory distress syndrome: a radical perspective

S Louie, B Halliwell, CE Cross - Advances in Pharmacology, 1996 - Elsevier
Publisher Summary Adult respiratory distress syndrome (ARDS) describes a life-threatening
acute lung injury involving a heterogenous group of critically ill patients with hypoxemic …