[HTML][HTML] Advances in mass spectrometry-based metabolomics for investigation of metabolites

JL Ren, AH Zhang, L Kong, XJ Wang - RSC advances, 2018 - pubs.rsc.org
Metabolomics is the systematic study of all the metabolites present within a biological
system, which consists of a mass of molecules, having a variety of physical and chemical …

Current state of the art of mass spectrometry-based metabolomics studies–a review focusing on wide coverage, high throughput and easy identification

Y Wang, S Liu, Y Hu, P Li, JB Wan - Rsc Advances, 2015 - pubs.rsc.org
Metabolomics aims at the comprehensive assessment of a wide range of endogenous
metabolites and attempts to identify and quantify the attractive metabolites in a given …

Overview of mass spectrometry-based metabolomics: opportunities and challenges

GAN Gowda, D Djukovic - Mass Spectrometry in Metabolomics: Methods …, 2014 - Springer
The field of metabolomics has witnessed an exponential growth in the last decade driven by
important applications spanning a wide range of areas in the basic and life sciences and …

Metabolite identification and quantitation in LC-MS/MS-based metabolomics

JF Xiao, B Zhou, HW Ressom - TrAC Trends in Analytical Chemistry, 2012 - Elsevier
Metabolomics aims at detection and quantitation of all metabolites in biological samples.
The presence of metabolites with a wide variety of physicochemical properties and different …

Current challenges and recent developments in mass spectrometry–based metabolomics

SL Collins, I Koo, JM Peters, PB Smith… - Annual review of …, 2021 - annualreviews.org
High-resolution mass spectrometry (MS) has advanced the study of metabolism in living
systems by allowing many metabolites to be measured in a single experiment. Although …

MET-IDEA: data extraction tool for mass spectrometry-based metabolomics

CD Broeckling, IR Reddy, AL Duran, X Zhao… - Analytical …, 2006 - ACS Publications
A current and significant limitation to metabolomics is the large-scale, high-throughput
conversion of raw chromatographically coupled mass spectrometry datasets into organized …

[HTML][HTML] Mass spectrometry strategies in metabolomics

Z Lei, DV Huhman, LW Sumner - Journal of Biological Chemistry, 2011 - ASBMB
MS has evolved as a critical component in metabolomics, which seeks to answer biological
questions through large-scale qualitative and quantitative analyses of the metabolome. MS …

Mass spectral databases for LC/MS-and GC/MS-based metabolomics: State of the field and future prospects

M Vinaixa, EL Schymanski, S Neumann… - TrAC Trends in …, 2016 - Elsevier
At present, mass spectrometry (MS)-based metabolomics has been widely used to obtain
new insights into human, plant, and microbial biochemistry; drug and biomarker discovery; …

Mass spectrometry‐based metabolomics: applications to biomarker and metabolic pathway research

A Zhang, H Sun, G Yan, P Wang… - Biomedical …, 2016 - Wiley Online Library
Mass spectrometry‐based metabolomics has become increasingly popular in molecular
medicine. High‐definition mass spectrometry (MS), coupled with pattern recognition …

From exogenous to endogenous: the inevitable imprint of mass spectrometry in metabolomics

EJ Want, A Nordström, H Morita… - Journal of proteome …, 2007 - ACS Publications
Mass spectrometry (MS) is an established technology in drug metabolite analysis and is now
expanding into endogenous metabolite research. Its utility derives from its wide dynamic …