Estrogen synthesis and signaling pathways during aging: from periphery to brain
J Cui, Y Shen, R Li - Trends in molecular medicine, 2013 - cell.com
Estrogens are the primary female sex hormones and play important roles in both
reproductive and non-reproductive systems. Estrogens can be synthesized in non …
reproductive and non-reproductive systems. Estrogens can be synthesized in non …
Tissue-specific effects of loss of estrogen during menopause and aging
The roles of estrogens have been best studied in the breast, breast cancers, and in the
female reproductive tract. However, estrogens have important functions in almost every …
female reproductive tract. However, estrogens have important functions in almost every …
Estrogen activates rapid signaling in the brain: role of estrogen receptor α and estrogen receptor β in neurons and glia
AJ Mhyre, DM Dorsa - Neuroscience, 2006 - Elsevier
The aging process is known to coincide with a decline in circulating sex hormone levels in
both men and women. Due to an increase in the average lifespan, a growing number of post …
both men and women. Due to an increase in the average lifespan, a growing number of post …
Brain sex matters: estrogen in cognition and Alzheimer's disease
R Li, J Cui, Y Shen - Molecular and cellular endocrinology, 2014 - Elsevier
Estrogens are the primary female sex hormones and play important roles in both
reproductive and non-reproductive systems. Estrogens can be synthesized in non …
reproductive and non-reproductive systems. Estrogens can be synthesized in non …
Estrogen receptors and the aging brain
S Maioli, K Leander, P Nilsson… - Essays in Biochemistry, 2021 - portlandpress.com
The female sex hormone estrogen has been ascribed potent neuroprotective properties. It
signals by binding and activating estrogen receptors that, depending on receptor subtype …
signals by binding and activating estrogen receptors that, depending on receptor subtype …
Estrogen and cancer
J Liang, Y Shang - Annual review of physiology, 2013 - annualreviews.org
Estrogen exhibits a broad spectrum of physiological functions ranging from regulation of the
menstrual cycle and reproduction to modulation of bone density, brain function, and …
menstrual cycle and reproduction to modulation of bone density, brain function, and …
Molecular mechanisms, physiological consequences and pharmacological implications of estrogen receptor action
T Barkhem, S Nilsson, JÅ Gustafsson - American Journal of …, 2004 - Springer
The estrogen receptors (ERs), ERα and ERβ, play a central role in mediating the biological
effects of estrogen. The transcription rate of estrogen target genes is determined by several …
effects of estrogen. The transcription rate of estrogen target genes is determined by several …
Estrogen receptors and endocrine diseases: lessons from estrogen receptor knockout mice
SO Mueller, KS Korach - Current opinion in pharmacology, 2001 - Elsevier
The estrogen receptors ERα and ERβ are the main mediators of estrogen action and
estrogens play an important role in a variety of aspects of physiology besides their well …
estrogens play an important role in a variety of aspects of physiology besides their well …
Estrogen receptors and human disease
BJ Deroo, KS Korach - The Journal of clinical investigation, 2006 - Am Soc Clin Investig
Estrogens influence many physiological processes in mammals, including but not limited to
reproduction, cardiovascular health, bone integrity, cognition, and behavior. Given this …
reproduction, cardiovascular health, bone integrity, cognition, and behavior. Given this …
Sex hormones and cardiometabolic health: role of estrogen and estrogen receptors
With increased life expectancy, women will spend over three decades of life
postmenopause. The menopausal transition increases susceptibility to metabolic diseases …
postmenopause. The menopausal transition increases susceptibility to metabolic diseases …