The gut-brain axis: how microbiota and host inflammasome influence brain physiology and pathology

A Rutsch, JB Kantsjö, F Ronchi - Frontiers in immunology, 2020 - frontiersin.org
The human microbiota has a fundamental role in host physiology and pathology. Gut
microbial alteration, also known as dysbiosis, is a condition associated not only with …

Gut microbiome-mediated regulation of neuroinflammation

JW Bostick, AM Schonhoff, SK Mazmanian - Current opinion in immunology, 2022 - Elsevier
Highlights•Microbe-derived molecules influence disease outcomes through diverse
mechanisms.•Short-chain fatty acid (SCFA) production in the gut can alter microglial …

The gut microbiome as a regulator of the neuroimmune landscape

LW Yu, G Agirman, EY Hsiao - Annual review of immunology, 2022 - annualreviews.org
The gut microbiome influences many host physiologies, spanning gastrointestinal function,
metabolism, immune homeostasis, neuroactivity, and behavior. Many microbial effects on …

Interactions between the microbiota, immune and nervous systems in health and disease

TC Fung, CA Olson, EY Hsiao - Nature neuroscience, 2017 - nature.com
The diverse collection of microorganisms that inhabit the gastrointestinal tract, collectively
called the gut microbiota, profoundly influences many aspects of host physiology, including …

[HTML][HTML] The microbiota-immune axis as a central mediator of gut-brain communication

TC Fung - Neurobiology of disease, 2020 - Elsevier
Intestinal inflammatory disorders are associated with neurophysiological and behavioral
symptoms. Conversely, many disorders of the central nervous system (CNS) are …

Boundaries and integration between microbiota, the nervous system, and immunity

AJ Macpherson, V Pachnis, M Prinz - Immunity, 2023 - cell.com
The enteric nervous system is largely autonomous, and the central nervous system is
compartmentalized behind the blood-brain barrier. Yet the intestinal microbiota shapes gut …

The impact of chronic intestinal inflammation on brain disorders: The microbiota-gut-brain axis

D Serra, LM Almeida, TCP Dinis - Molecular Neurobiology, 2019 - Springer
It has been shown that the gut microbiota plays a crucial role in the maintenance of intestinal
homeostasis. Additionally, it has been demonstrated that dysbiosis is closely correlated with …

Gut microbiota interact with the brain through systemic chronic inflammation: implications on neuroinflammation, neurodegeneration, and aging

Y Mou, Y Du, L Zhou, J Yue, X Hu, Y Liu… - Frontiers in …, 2022 - frontiersin.org
It has been noticed in recent years that the unfavorable effects of the gut microbiota could
exhaust host vigor and life, yet knowledge and theory are just beginning to be established …

The impact of gut microbiota disorders on the blood–brain barrier

W Tang, H Zhu, Y Feng, R Guo… - Infection and Drug …, 2020 - Taylor & Francis
The gut microbiota is symbiotic with the human host and has been extensively studied in
recent years resulting in increasing awareness of the effects of the gut microbiota on human …

Impact of Microbiome–Brain Communication on Neuroinflammation and Neurodegeneration

I Stolzer, E Scherer, P Süß, V Rothhammer… - International Journal of …, 2023 - mdpi.com
The gut microbiome plays a pivotal role in maintaining human health, with numerous studies
demonstrating that alterations in microbial compositions can significantly affect the …