Meiotic maturation and cumulus expansion are essential for the generation of a
developmentally competent gamete, and both processes can be recapitulated in vitro. We …

Introduction Morphokinetic analysis using a closed time-lapse monitoring system
(EmbryoScope+™) provides quantitative metrics of meiotic progression and cumulus …

STUDY QUESTION Is there an association between morphokinetic variables of meiotic
maturation and the severity of aneuploidy following in vitro maturation (IVM) in the mouse …

Purpose To investigate the role of cumulus cell contact during oocyte maturation on meiotic
spindle assembly and the acquisition of developmental competence. Methods Cumulus …

Maturation of the mammalian oocyte involves hormone-induced meiotic cell cycle
progression from prophase I to metaphase II and extrusion of the first polar body (PB). In this …

Mammalian oocyte maturation and cumulus expansion are hormone-induced
contemporaneous processes that involve changes in cumulus cell shape and in the …

BACKGROUND In a growth phase occurring during most of folliculogenesis, the oocyte
produces and accumulates molecules and organelles that are fundamental for the …

In most mammals, meiotic maturation is initiated near the time of biih when oogonia cease
proliferating and enter prophase I of meiosis. The germ cells, now referred to as oocytes …

Oocyte-cumulus cell bidirectional communication is essential for normal development of the
oocyte and cumulus cells (CCs) within the follicle. We showed recently that addition of …

Mammalian oocytes resume meiosis spontaneously after removal from the ovarian follicle.
We tested the effects of a 2-h prematuration treatment (Pre-IVM) with forskolin (FSK) and 3 …