GERD is a common condition worldwide. Key mechanisms of disease include abnormal
oesophagogastric junction structure and function, and impaired oesophageal clearance. A …

Clinical history, questionnaire data and response to antisecretory therapy are insufficient to
make a conclusive diagnosis of GERD in isolation, but are of value in determining need for …

The purpose of this review is to outline the recent developments in the field of
extraesophageal reflux disease and provide clinically relevant recommendations. The …

It is neither practical nor necessary to initiate a diagnostic evaluation of every patient with
symptoms of GERD. Management, by and large, is focused on empiric therapy, with lifestyle …

Background & Aims As many as one-half of all patients with suspected gastroesophageal
reflux disease (GERD) do not derive benefit from acid suppression. This review outlines a …

The Lyon Consensus provides conclusive criteria for and against the diagnosis of gastro-
oesophageal reflux disease (GERD), and adjunctive metrics that consolidate or refute GERD …

Gastroesophageal reflux disease (GERD) is a complex disorder with heterogeneous
symptoms and a multifaceted pathogenetic basis, which prevent a simple diagnostic …

Up to 40% of patients with symptoms suspicious of gastroesophageal reflux disease (GERD)
do not respond completely to proton pump inhibitor (PPI) therapy. The term “refractory …

Background The diagnosis of gastro‐oesophageal reflux disease (GERD) remains a
challenge as both invasive methods and symptom‐based strategies have limitations. The …

Esophageal symptoms are common and may indicate the presence of gastroesophageal
reflux disease (GERD), structural processes, motor dysfunction, behavioral conditions, or …