[HTML][HTML] From oncolytic peptides to oncolytic polymers: A new paradigm for oncotherapy

H Liu, W Shen, W Liu, Z Yang, D Yin, C Xiao - Bioactive Materials, 2024 - Elsevier
Traditional cancer therapy methods, especially those directed against specific intracellular
targets or signaling pathways, are not powerful enough to overcome tumor heterogeneity …

Design of polymeric carriers for intracellular peptide delivery in oncology applications

S Lv, M Sylvestre, AN Prossnitz, LF Yang… - Chemical …, 2021 - ACS Publications
In recent decades, peptides, which can possess high potency, excellent selectivity, and low
toxicity, have emerged as promising therapeutics for cancer applications. Combined with an …

Robust and smart polypeptide-based nanomedicines for targeted tumor therapy

C Deng, Q Zhang, J Guo, X Zhao, Z Zhong - Advanced drug delivery …, 2020 - Elsevier
Nanomedicines based on synthetic polypeptides are among the most versatile and
advanced platforms for tumor therapy. Notably, several polypeptide-based nanodrugs are …

Functionalized peptide-based nanoparticles for targeted cancer nanotherapeutics: A state-of-the-art review

R Sharma, SJ Borah, Bhawna, S Kumar, A Gupta… - ACS …, 2022 - ACS Publications
Cancer mortality is increasing at an alarming rate across the globe. Albeit, many
therapeutics are available commercially, they are not effective and have no cure up to today …

Cancer nanomedicines based on synthetic polypeptides

H Sun, X Gu, Q Zhang, H Xu, Z Zhong… - …, 2019 - ACS Publications
Nanomedicines are deemed as the most promising treatment modality for malignant
cancers. Particularly, cancer nanomedicines based on synthetic polypeptides have gained …

Peptide‐based supramolecular nanodrugs as a new generation of therapeutic toolboxes against cancer

R Chang, Q Zou, R Xing, X Yan - Advanced Therapeutics, 2019 - Wiley Online Library
Peptides are an important class of biomaterials that are widely used in the biomedical field
due to their biocompatibility, bioavailability, and structural diversity. They self‐assemble into …

Peptides in cancer nanomedicine: drug carriers, targeting ligands and protease substrates

XX Zhang, HS Eden, X Chen - Journal of controlled release, 2012 - Elsevier
Peptides are attracting increasing attention as therapeutic agents, as the technologies for
peptide development and manufacture continue to mature. Concurrently, with booming …

[HTML][HTML] Peptide-decorated polymeric nanomedicines for precision cancer therapy

H Sun, Y Dong, J Feijen, Z Zhong - Journal of controlled release, 2018 - Elsevier
The advancement of tissue and cell-specific drug delivery systems is a key to precision
cancer therapy. Peptides, with easy synthesis, low immunogenicity and biological functions …

Peptide-based cancer therapy: opportunity and challenge

D Wu, Y Gao, Y Qi, L Chen, Y Ma, Y Li - Cancer letters, 2014 - Elsevier
Cancer is one of the leading causes of death worldwide. Conventional cancer therapies
mainly focus on mass cell killing without high specificity and often cause severe side effects …

[图书][B] Polymer therapeutics for cancer: current status and future challenges

R Satchi-Fainaro, R Duncan, CM Barnes - 2006 - Springer
Drug delivery systems for cancer therapeutics have revolutionized medicine. Delivery
systems have improved the efficacy and reduced the toxicity of current therapies and …