[HTML][HTML] From oncolytic peptides to oncolytic polymers: A new paradigm for oncotherapy
H Liu, W Shen, W Liu, Z Yang, D Yin, C Xiao - Bioactive Materials, 2024 - Elsevier
Traditional cancer therapy methods, especially those directed against specific intracellular
targets or signaling pathways, are not powerful enough to overcome tumor heterogeneity …
targets or signaling pathways, are not powerful enough to overcome tumor heterogeneity …
Design of polymeric carriers for intracellular peptide delivery in oncology applications
In recent decades, peptides, which can possess high potency, excellent selectivity, and low
toxicity, have emerged as promising therapeutics for cancer applications. Combined with an …
toxicity, have emerged as promising therapeutics for cancer applications. Combined with an …
Robust and smart polypeptide-based nanomedicines for targeted tumor therapy
C Deng, Q Zhang, J Guo, X Zhao, Z Zhong - Advanced drug delivery …, 2020 - Elsevier
Nanomedicines based on synthetic polypeptides are among the most versatile and
advanced platforms for tumor therapy. Notably, several polypeptide-based nanodrugs are …
advanced platforms for tumor therapy. Notably, several polypeptide-based nanodrugs are …
Functionalized peptide-based nanoparticles for targeted cancer nanotherapeutics: A state-of-the-art review
Cancer mortality is increasing at an alarming rate across the globe. Albeit, many
therapeutics are available commercially, they are not effective and have no cure up to today …
therapeutics are available commercially, they are not effective and have no cure up to today …
Cancer nanomedicines based on synthetic polypeptides
Nanomedicines are deemed as the most promising treatment modality for malignant
cancers. Particularly, cancer nanomedicines based on synthetic polypeptides have gained …
cancers. Particularly, cancer nanomedicines based on synthetic polypeptides have gained …
Peptide‐based supramolecular nanodrugs as a new generation of therapeutic toolboxes against cancer
R Chang, Q Zou, R Xing, X Yan - Advanced Therapeutics, 2019 - Wiley Online Library
Peptides are an important class of biomaterials that are widely used in the biomedical field
due to their biocompatibility, bioavailability, and structural diversity. They self‐assemble into …
due to their biocompatibility, bioavailability, and structural diversity. They self‐assemble into …
Peptides in cancer nanomedicine: drug carriers, targeting ligands and protease substrates
XX Zhang, HS Eden, X Chen - Journal of controlled release, 2012 - Elsevier
Peptides are attracting increasing attention as therapeutic agents, as the technologies for
peptide development and manufacture continue to mature. Concurrently, with booming …
peptide development and manufacture continue to mature. Concurrently, with booming …
[HTML][HTML] Peptide-decorated polymeric nanomedicines for precision cancer therapy
The advancement of tissue and cell-specific drug delivery systems is a key to precision
cancer therapy. Peptides, with easy synthesis, low immunogenicity and biological functions …
cancer therapy. Peptides, with easy synthesis, low immunogenicity and biological functions …
Peptide-based cancer therapy: opportunity and challenge
D Wu, Y Gao, Y Qi, L Chen, Y Ma, Y Li - Cancer letters, 2014 - Elsevier
Cancer is one of the leading causes of death worldwide. Conventional cancer therapies
mainly focus on mass cell killing without high specificity and often cause severe side effects …
mainly focus on mass cell killing without high specificity and often cause severe side effects …
[图书][B] Polymer therapeutics for cancer: current status and future challenges
R Satchi-Fainaro, R Duncan, CM Barnes - 2006 - Springer
Drug delivery systems for cancer therapeutics have revolutionized medicine. Delivery
systems have improved the efficacy and reduced the toxicity of current therapies and …
systems have improved the efficacy and reduced the toxicity of current therapies and …