Vascular endothelial growth factor 165/bone morphogenetic protein improves osteoblast injury under hypoxic and reoxygenated conditions

Y Zhao, Y Zhang, J Ma, X He - Chinese Journal of Tissue Engineering …, 2024 - cjter.com
BACKGROUND: It has been found that vascular endothelial growth factor 165 and bone
morphogenetic proteins interact with each other during hypoxia-reoxygenation and are …

Expression of hypoxia-inducible factor 1 alpha and core binding factor alpha 1 in rat models of femoral fracture combined with cerebral trauma

X Bo, L Xu, X Luo, F Liu, W Huang, Y Guo, L Ma… - Chinese Journal of …, 2015 - cjter.com
BACKGROUND: The low oxygen environment after femoral fracture and cerebral trauma will
induce series of related cytokines expression, including hypoxia-inducible factor 1α and …

Vascular endothelial growth factor combined with mutant hypoxia-inducible factor 1alpha promotes angiogenesis

L Hu, J Wang, Z Wang, J Xie, D Chen… - Chinese Journal of Tissue …, 2019 - cjter.com
BACKGROUND: Transcription and translation of vascular endothelial growth factor has
been shown to be increased under ischemic and hypoxic conditions, which effectively …

Relationship between hypoxia-inducible factors and bone homeostasis disorders

H Li, L Yang, X Jin - Chinese Journal of Tissue Engineering Research, 2022 - cjter.com
BACKGROUND: Hypoxia-inducible factor is a key gene expression regulator in the bone
hypoxia microenvironment. It is of great significance to understand the mechanism of …

Expression of vascular endothelial growth factor in bony callus of patients with fracture combined with head injury versus simple fracture patients and its clinical …

J LI, Z Guo, J Han, F LI, J San… - Chinese Journal of …, 2009 - pesquisa.bvsalud.org
BACKGROUND: Clinical evidence have proved that heterotopic ossification is easily present
in bony callus of patients with fracture combined with head injury, and the healing of bone …

Viability of osteoblasts under cell hypoxia condition

C Wu, WW Zheng, M Yang - Zhonghua yi xue za zhi, 2017 - europepmc.org
Objective: To investigate the effects of hypoxia condition and hypoxia-reoxygenation
condition on the cell viability, apoptosis rate and gene expression of osteoblasts cultured in …

Hypoxia and VEGF up-regulate BMP-2 mRNA and protein expression in microvascular endothelial cells: implications for fracture healing

PJ Bouletreau, SM Warren, JA Spector… - Plastic and …, 2002 - journals.lww.com
The endothelium is a metabolically active secretory tissue, capable of responding to a wide
array of environmental stimuli. Hypoxia and vascular endothelial growth factor (VEGF) are …

Chondrogenic phenotype differentiation of bone marrow mesenchymal stem cells induced by bone morphogenetic protein 2 under hypoxic microenvironment in vitro

X Liao, L Wu, M Fu, D He, Y Gu, W Chen… - … xiu fu Chong Jian wai ke …, 2012 - europepmc.org
Objective To investigate the role of bone morphogenetic protein 2 (BMP-2) combined with
hypoxic microenvironment in chondrogenic phenotype differentiation of bone marrow …

Combination of bone morphogenetic protein 2 and mutant hypoxia-inducible factor 1α alpha repairs steroid-induced avascular necrosis of the femoral head

L Hu, J Wang, Z Wang, J Xie, D Chen… - Chinese Journal of Tissue …, 2018 - cjter.com
Abstract BACKGROUND: Bonemorphogeneticprotein2 (BMP-2) istheuniquegrowthfactorthatindependentlyi…
, butits promotingangiogenesisisweak, andcannotproducesufficientcapillariesinthe …

Effects of different stress force stimulations on the expression of vascular endothelial growth factor in Beagle dogs in the repairing process of osteonecrosis of the …

CH Liu, DW Zhao, BJ Wang - Zhonghua yi xue za zhi, 2012 - europepmc.org
Objective To explore the changes and its significance of the expression of vascular
endothelial growth factor (VEGF) protein and messenger RNA in the Beagle dogs femoral …