Genetic and Clinicopathologic Characteristics of Papillary Thyroid Carcinoma in the Chinese Population: High BRAF Mutation Allele Frequency, Multiple Driver Gene Mutations …

Z Wang, P Tang, S Hua, J Gao, B Zhang… - OncoTargets and …, 2022 - Taylor & Francis
Purpose To describe the genetic landscape and clinical characteristics of Chinese patients
diagnosed with papillary thyroid cancer (PTC) and to determine which high-risk genetic …

[HTML][HTML] The changing characteristics and molecular profiles of papillary thyroid carcinoma over time: a systematic review

HG Vuong, AMA Altibi, AH Abdelhamid, PUD Ngoc… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Background The genetic alterations of papillary thyroid carcinoma (PTC) have been
reported to change over the past few decades. We performed this systematic review to …

Relevance and clinicopathologic relationship of BRAF V600E, TERT and NRAS mutations for papillary thyroid carcinoma patients in Northwest China

M Huang, C Yan, J Xiao, T Wang, R Ling - Diagnostic pathology, 2019 - Springer
Background To determine the relevance of the single or combination mutations of BRAF
V600E, TERT, and NRAS genes and the clinicopathologic relationship in papillary thyroid …

[HTML][HTML] Association between BRAF and RAS mutations, and RET rearrangements and the clinical features of papillary thyroid cancer

J Ming, Z Liu, W Zeng, Y Maimaiti, Y Guo… - … journal of clinical and …, 2015 - ncbi.nlm.nih.gov
Objective: To evaluate the significance of BRAF V600E and Ras mutations, and RET
rearrangements in papillary thyroid cancer (PTC) in the South central region of China …

Genetic landscape of papillary thyroid carcinoma in the Chinese population

J Liang, W Cai, D Feng, H Teng, F Mao… - The Journal of …, 2018 - Wiley Online Library
Improvement in the clinical outcome of human cancers requires characterization of the
genetic alterations underlying their pathogenesis. Large‐scale genomic and transcriptomic …

Prognostic implication of BRAF and TERT promoter mutation combination in papillary thyroid carcinoma—a meta‐analysis

HG Vuong, AMA Altibi, UNP Duong… - Clinical …, 2017 - Wiley Online Library
Introduction The use of molecular markers, especially BRAF and TERT promoter mutations,
for risk stratification in papillary thyroid carcinoma (PTC) is subject to continuing debate. In …

[HTML][HTML] Genetic alterations and their clinical implications in high-recurrence risk papillary thyroid cancer

MY Lee, BM Ku, HS Kim, JY Lee… - … : Official Journal of …, 2017 - synapse.koreamed.org
Purpose Papillary thyroid carcinomas (PTCs) frequently involve genetic alterations. The
objective of this study was to investigate genetic alterations and further explore the …

Genomic characterization of high-recurrence risk papillary thyroid carcinoma in a southern Chinese population

M Li, H Jia, Q Qian, P Wen, C Chen, Y Hua, K Wang… - Diagnostic …, 2020 - Springer
Background The objective of this study was to investigate genetic variations and the
relationships between these genetic variations and clinicopathological features of high …

[HTML][HTML] Multi-gene assay and clinical characteristics research in papillary thyroid carcinoma

C Deng, S Li, Z Yang, Y Dou, D Hu, J Zhu, D Wang… - Gland …, 2021 - ncbi.nlm.nih.gov
Background To investigate the significance of multi-gene assay in papillary thyroid
carcinoma (PTC) patients in clinical practice. Methods From April to December 2019 …

BRAF V600E and TERT Promoter Mutations Cooperatively Identify the Most Aggressive Papillary Thyroid Cancer With Highest Recurrence

M Xing, R Liu, X Liu, AK Murugan, G Zhu… - Journal of clinical …, 2014 - ascopubs.org
Purpose To investigate the prognostic value of the BRAF V600E mutation and the recently
identified TERT promoter mutation chr5: 1,295,228 C> T (C228T), individually and in their …