Purpose: In the present study, biodegradable poly (3-hydroxybutyrate-co-3-
hydroxyvalerate)(PHBV) nanoparticles (NPs) containing insulin were loaded in sodium …

Methods NIPAAm-MAA-HEM copolymers were synthesized by radical chain reaction with
86: 4: 10 (5% w/v) ratios respectively. Reaction was carried out in 1, 4-Dioxane under …

Oral insulin (INS) is predicted to have the most therapeutic advantages in treating diabetes
to repress hepatic glucose production through its potential to mimic the endogenous insulin …

Purpose Oral delivery of peptide/protein is quite difficult due to physiological barriers.
Encapsulation of these drugs in the suitable biopolymeric matrix could protect the drug as …

In the current study, a novel interpenetrating polymer network (IPN) hydrogel bead was
developed by encapsulation of antidiabetic drug glipizide using sodium alginate (SAL) and …

Oral delivery of insulin has always been a challenging task due to harsh gut environment
involving variable pH and peptidase actions. Currently, no Food and Drug Administration …

Chitosan (CS)–polyvinyl alcohol (PVA) blend hydrogels were prepared using
glutaraldehyde as the cross-linking agent. The obtained hydrogels, which have the …

The purpose of this research was the fabrication, statistical optimization, and in vitro
characterization of insulin-loaded poly (hydroxybutyrate-co-hydroxyvalerate)(PHBV) …

Long-term and daily subcutaneous injections of insulin for the treatment of insulin-
dependent diabetic patients often lead to poor patient compliance and undesired …

The application of poly (hydroxybutyrate-co-hydroxyhexanoate)(PHBHHx) for sustained and
controlled delivery of hydrophilic insulin was made possible by preparing insulin …