[HTML][HTML] The Polyvalent Role of NF90 in RNA Biology

G Grasso, R Kiernan - International Journal of Molecular Sciences, 2022 - mdpi.com
Double-stranded RNA-binding proteins (dsRBPs) are major players in the regulation of
gene expression patterns. Among them, Nuclear Factor 90 (NF90) has a plethora of well …

[HTML][HTML] NF90 interacts with components of RISC and modulates association of Ago2 with mRNA

G Grasso, C Akkawi, C Franckhauser, R Nait-Saidi… - BMC biology, 2022 - Springer
Abstract Background Nuclear factor 90 (NF90) is a double-stranded RNA-binding protein
involved in a multitude of different cellular mechanisms such as transcription, translation …

[HTML][HTML] NF90 in posttranscriptional gene regulation and microRNA biogenesis

K Masuda, Y Kuwano, K Nishida, K Rokutan… - International journal of …, 2013 - mdpi.com
Gene expression patterns are effectively regulated by turnover and translation regulatory
(TTR) RNA-binding proteins (RBPs). The TTR-RBPs control gene expression at …

NF90 modulates processing of a subset of human pri-miRNAs

G Grasso, T Higuchi, V Mac, J Barbier… - Nucleic Acids …, 2020 - academic.oup.com
MicroRNAs (miRNAs) are predicted to regulate the expression of> 60% of mammalian
genes and play fundamental roles in most biological processes. Deregulation of miRNA …

The NF90-NF45 complex functions as a negative regulator in the microRNA processing pathway

S Sakamoto, K Aoki, T Higuchi, H Todaka… - … and cellular biology, 2009 - Taylor & Francis
The positive regulatory machinery in the microRNA (miRNA) processing pathway is
relatively well characterized, but negative regulation of the pathway is largely unknown …

[HTML][HTML] Systematic identification of NF90 target RNAs by iCLIP analysis

V Lodde, M Floris, R Munk, JL Martindale, D Piredda… - Scientific Reports, 2022 - nature.com
RNA-binding proteins (RBPs) interact with and determine the fate of many cellular RNAs
directing numerous essential roles in cellular physiology. Nuclear Factor 90 (NF90) is an …

A negative feedback loop between nuclear factor 90 (NF90) and an anti-oncogenic microRNA, miR-7

T Higuchi, K Morisawa, H Todaka, S Lai, E Chi… - Biochemical and …, 2018 - Elsevier
Alterations in microRNAs (miRNAs) levels deeply correlate with tumorigenesis. However,
the molecular mechanism for the regulation of the miRNA production in tumors is not fully …

The latest progress on miR‐374 and its functional implications in physiological and pathological processes

H Bian, Y Zhou, D Zhou, Y Zhang… - Journal of cellular and …, 2019 - Wiley Online Library
Non‐coding RNAs (ncRNAs) have been emerging players in cell development,
differentiation, proliferation and apoptosis. Based on their differences in length and structure …

Coordinated action of two double-stranded RNA binding motifs and an RGG motif enables nuclear factor 90 to flexibly target different RNA substrates

T Schmidt, P Knick, H Lilie, S Friedrich, RP Golbik… - Biochemistry, 2016 - ACS Publications
The mechanisms of how RNA binding proteins (RBP) bind to and distinguish different RNA
molecules are yet uncertain. Here, we performed a comprehensive analysis of the RNA …

Ilf3 and NF90 functions in RNA biology

S Castella, R Bernard, M Corno… - Wiley …, 2015 - Wiley Online Library
Double‐stranded RNA‐binding proteins (DRBPs) are known to regulate many processes of
RNA metabolism due, among others, to the presence of double‐stranded RNA (dsRNA) …