Oral delivery of anticancer drugs: challenges and opportunities

K Thanki, RP Gangwal, AT Sangamwar… - Journal of controlled …, 2013 - Elsevier
The present report focuses on the various aspects of oral delivery of anticancer drugs. The
significance of oral delivery in cancer therapeutics has been highlighted which principally …

[HTML][HTML] Nanomedicine for increasing the oral bioavailability of cancer treatments

A Parodi, P Buzaeva, D Nigovora, A Baldin… - Journal of …, 2021 - Springer
Oral administration is an appealing route of delivering cancer treatments. However, the
gastrointestinal tract is characterized by specific and efficient physical, chemical, and …

Advances in delivery of chemotherapeutic agents for cancer treatment

A Yadav, S Singh, H Sohi, S Dang - AAPS PharmSciTech, 2022 - Springer
Presently, most of the treatment strategies for cancer are focused on the surgical removal of
cancerous tumors, along with physical and chemical treatment such as radiotherapy and …

Overcoming the intestinal barrier: a look into targeting approaches for improved oral drug delivery systems

Y Xu, N Shrestha, V Préat, A Beloqui - Journal of controlled release, 2020 - Elsevier
Oral drug administration is one of the most preferred and simplest routes among both
patients and formulation scientists. Nevertheless, orally delivery of some of the most widely …

Pharmaceutical nanotechnology for oral delivery of anticancer drugs

L Mei, Z Zhang, L Zhao, L Huang, XL Yang… - Advanced drug delivery …, 2013 - Elsevier
Oral chemotherapy is an important topic in the 21st century medicine, which may radically
change the current regimen of chemotherapy and greatly improve the quality of life of the …

Improving oral absorption via drug-loaded nanocarriers: absorption mechanisms, intestinal models and rational fabrication

MA Shahbazi, HA Santos - Current drug metabolism, 2013 - ingentaconnect.com
Although it is acknowledged that the main impediment of orally administered therapeutic
agents is their extensive and changeable pre-systemic metabolism, low absorption and …

[HTML][HTML] Nanotechnology-based biopolymeric oral delivery platforms for advanced cancer treatment

VT Chivere, PPD Kondiah, YE Choonara, V Pillay - Cancers, 2020 - mdpi.com
Routes of drug administration and their corresponding physiochemical characteristics play
major roles in drug therapeutic efficiency and biological effects. Each route of delivery has …

Oral delivery of anticancer drugs III: formulation using drug delivery systems

S Mazzaferro, K Bouchemal, G Ponchel - Drug discovery today, 2013 - Elsevier
In the past few years, the growth of nanometric size drug delivery systems (DDS) has burst
into challenging innovations enabling real progresses to achieve oral delivery of anticancer …

Nanocarriers for anticancer drugs-new trends in nanomedicine

J Drbohlavova, J Chomoucka, V Adam… - Current drug …, 2013 - ingentaconnect.com
This review provides a brief overview of the variety of carriers employed for targeted drug
delivery used in cancer therapy and summarizes advantages and disadvantages of each …

Nanotherapeutics in oral and parenteral drug delivery: Key learnings and future outlooks as we think small

P Tyagi, JA Subramony - Journal of Controlled Release, 2018 - Elsevier
Nanotechnology ushered the field of medicine in to a new era. Miniaturization, increased
surface area, and the unique physicochemical properties in the nano dimension were …