A cell culturing platform for modeling myelination in vitro comprises first cell chambers
(102a, 102b) for containing somas of neuronal cells, a process chamber (103) connected to …

A device for cell culture, in particular of neuronal cells, including: a substrate defining a first
microfluidic chamber to be seeded with a first cell culture, and at least a second microfluidic …

Provided is a method of inducing the differentiation of a stem cell into nerve progenitor cells,
comprising the step (1) of forming homogenous aggregates of stem cells in a serum-free …

The invention provides methods for producing myelin form ing cells from multipotent self-
renewing central nervous system neural stem cells as well as methods of using one or more …

A method for simulating the neuroinflammatory response in brains comprising the steps of
providing a microfluidic device for regulating microgliosis comprising a base, a central …

Abstract A Myelin Basic Protein-luciferase bioimaging noninvasive model to visualize and
quantify demyelination and remyelination events in the CNS at transcriptional level in vivo is …

Primary microglia, in either mono-culture or co-culture with neurons or astrocytes, are a
powerful tool for studying mechanisms underlying microglial inflammatory responses and …

During peripheral nerve myelination in the early postnatal period, the matching of SC and
axon numbers is regulated by SC apoptosis, resulting in the mature 1: 1 relationship …

Abstract A Myelin Basic Protein-luciferase bioimaging noninvasive model to visualize and
quantify demyelination and remyelination events in the CNS at transcriptional level in vivo is …

The invention relates to at least one novel neural cell differ entiation medium for the
production of neural cells from at least one precursor cell capable of lineage specific differen …