Recent developments in synthetic biology, combined with continued progress in systems
biology and metabolic engineering, have enabled the engineering of microorganisms to …

The richness and versatility of biological systems make them ideally suited to solve some of
the world's most significant challenges, such as converting cheap, renewable resources into …

Many drugs and drug precursors found in natural organisms are rather difficult to synthesize
chemically and to extract in large amounts. Metabolic engineering is playing an increasingly …

Synthetic biology can significantly advance metabolic engineering by contributing tools
(minimal hosts, vectors, genetic controllers, characterized enzymes). The development of …

Artemisinin, an endoperoxidized sesquiterpene originally extracted from the medicinal plant
Artemisia annua L., is a potent malaria-killing agent. Due to the urgent demand and short …

Despite considerable efforts by multiple governmental and non-governmental organizations
to increase access to artemisinin-based combination therapies (ACTs), these life-saving …

Malaria represents one of the most medically and economically debilitating diseases
present in the world today. Fortunately, there exists a highly effective treatment based on the …

Artemisinin the sesquiterpene endoperoxide lactone extracted from the herb Artemisia
annua, remains the basis for the current preferred treatment against the malaria parasite …

Active pharmaceutical ingredients are either extracted from biological sources—where they
are synthesized in complex, dynamic environments—or prepared in stepwise chemical …

The antimalarial drug artemisinin is a natural product produced by the plant Artemisia
annua. Extracts of A. annua have been used in Chinese herbal medicine for over two …