Use of Embryonic Stem Cell-Derived Endothelial Cells as a Cell Source to Generate Vessel Structures in Vitro

KE McCloskey, ME Gilroy, RM Nerem - Tissue engineering, 2005 - liebertpub.com
Embryonic stem (ES) cells could potentially serve as an excellent cell source for various
applications in regenerative medicine and tissue engineering. Our laboratory is particularly …

Tissue engineering of blood vessels with endothelial cells differentiated from mouse embryonic stem cells

G Shen, HC Tsung, CF Wu, XY Liu, X Wang, W Liu… - Cell research, 2003 - nature.com
Endothelial cells (TEC 3 cells) derived from mouse embryonic stem (ES) cells were used as
seed cells to construct blood vessels. Tissue engineered blood vessels were made by …

Purified and proliferating endothelial cells derived and expanded in vitro from embryonic stem cells

KE McCloskey, I Lyons, RR Rao, SL Stice… - Endothelium, 2003 - Taylor & Francis
Embryonic stem (ES) cells serve as an excellent in vitro system for studying differentiation
events and for developing methods of generating various specialized cells for future …

Derivation of endothelial cells from human embryonic stem cells by directed differentiation: analysis of microRNA and angiogenesis in vitro and in vivo

NM Kane, M Meloni, HL Spencer… - … , and vascular biology, 2010 - Am Heart Assoc
Objective—To develop an embryoid body-free directed differentiation protocol for the rapid
generation of functional vascular endothelial cells derived from human embryonic stem cells …

Vascular engineering using human embryonic stem cells

D Hanjaya‐Putra, S Gerecht - Biotechnology progress, 2009 - Wiley Online Library
Engineering vascularized tissue constructs remains a major problem in regenerative
medicine. The formation of such a microvasculature—like the vasculogenesis in early …

In vitro derivation and expansion of endothelial cells from embryonic stem cells

KE McCloskey, SL Stice, RM Nerem - Embryonic Stem Cell Protocols …, 2006 - Springer
Vascular endothelial cells or endothelial progenitor cells derived from stem cells could
potentially lead to a variety of clinically relevant applications, including cell-based therapies …

Murine embryonic stem cell in vitro differentiation: applications to the study of vascular development

O Feraud, D Vittet - Histology and histopathology, 2003 - digitum.um.es
The present review summarizes knowledge accumulated during the last decade concerning
in vitro endothelial differentiation from embryonic stem (ES) cells. There is now growing …

Endothelial stem cells and precursors for tissue engineering: cell source, differentiation, selection, and application

S Kim, H Von Recum - Tissue Engineering Part B: Reviews, 2008 - liebertpub.com
Endothelial cells are of great interest because of their potential in cell therapy for vascular
diseases and ischemic tissue, tissue engineering for vascular grafts and vascularized tissue …

Mesenchymal stem cells can be differentiated into endothelial cells in vitro

J Oswald, S Boxberger, B Jørgensen, S Feldmann… - Stem …, 2004 - academic.oup.com
Human bone marrow‐derived mesenchymal stem cells (MSCs) have the potential to
differentiate into mesenchymal tissues like osteocytes, chondrocytes, and adipocytes in vivo …

Endothelial cells derived from human embryonic stem cells

S Levenberg, JS Golub, M Amit… - Proceedings of the …, 2002 - National Acad Sciences
Human embryonic stem cells have the potential to differentiate into various cell types and,
thus, may be useful as a source of cells for transplantation or tissue engineering. We …