The sympathetic nervous system is central for the neurohumoral regulation of the
cardiovascular system and is largely involved in many cardiovascular diseases affecting …

Catecholamines play a key role in the regulation of cardiovascular function, classically
through ß 1/2-adrenoreceptors (AR) activation. After ß 3-AR cloning in the late 1980s …

The third isotype of beta-adrenoreceptors (β3-AR) has recently come (back) into focus after
the observation of its expression in white and beige human adipocytes and its implication in …

Abstract β-Adrenoceptors of the β 1 and β 2 subtypes classically mediate the effects of
catecholamines on the contractility of cardiac muscle and the relaxation of vascular smooth …

β3-Adrenoceptors (β3-ARs) are located not only on the plasma membrane of both white and
brown adipocytes, but also exist in human heart, gall bladder, gastrointestinal tract, prostate …

Catecholamines released by the orthosympathetic system play a major role in the short-and
long-term regulation of cardiovascular function. Beta1-and beta2-adrenoreceptors (ARs) …

β-adrenergic receptors have been subdivided into three types: β1-, β2-and β3-adrenergic
receptors. β1-adrenergic receptors are predominant in the heart, β2-adrenergic receptors–in …

The sympathetic system is central in the understanding of numerous physiological and
physiopathological phenomena. During the last decade, the characterization of a new β …

Beta3-adrenoreceptors (B3AR) are traditionally known as metabolic receptors in adipose
tissue, but came into focus in the cardiovascular field after our demonstration of their …

Although ligand-free, constitutive β2-adrenergic receptor (AR) signaling has been
demonstrated in naive cell lines and in transgenic mice overexpressing cardiac β2-AR, it is …