[HTML][HTML] Blood–brain barrier permeability study of potential neuroprotective compounds recovered from plants and agri-food by-products

JD Sánchez-Martínez, A Valdés, R Gallego… - Frontiers in …, 2022 - frontiersin.org
Plants and agri-food by-products represent a wide and renewable source of bioactive
compounds with neuroprotective properties. In this research, various green extraction …

In vitro study of the blood–brain barrier transport of natural compounds recovered from agrifood by-products and microalgae

JD Sánchez-Martínez, AR Garcia… - International Journal of …, 2022 - mdpi.com
Agrifood by-products and microalgae represent a low-cost and valuable source of bioactive
compounds with neuroprotective properties. However, the neuroprotective effectiveness of …

Rapid screening of brain-penetrable antioxidants from natural products by blood-brain barrier specific permeability assay combined with DPPH recognition

J Zhu, X Yi, J Zhang, S Chen, Y Wu - Journal of Pharmaceutical and …, 2018 - Elsevier
Screening brain-penetrable antioxidants from natural products is a promising way for
neuroprotective drug discovery. However, there is no screening methodology enables …

[HTML][HTML] Neuroprotective Potential of Tamarillo (Cyphomandra betacea) Epicarp Extracts Obtained by Sustainable Extraction Process

ZJ Suárez-Montenegro, D Ballesteros-Vivas… - Frontiers in …, 2021 - frontiersin.org
Tamarillo (Cyphomandra betacea (Cav.) Sendt.), or tree tomato, is a tropical fruit from the
Andean region of South America; it is highly rich in vitamins, minerals, and polyphenolic …

Cognitive Enhancing and Antioxidative Potentials of Velvet Beans (Mucuna pruriens) and Horseradish (Moringa oleifera) Seeds Extracts: A Comparative Study

SA Adefegha, G Oboh, SI Oyeleye… - Journal of Food …, 2017 - Wiley Online Library
Velvet beans and Horseradish seeds are widely consumed as food, and use in folklore for
the treatment of cognitive dysfunction although with limited information on their mechanisms …

Phenolic compounds that cross the blood–brain barrier exert positive health effects as central nervous system antioxidants

D Velásquez-Jiménez, DA Corella-Salazar… - Food & Function, 2021 - pubs.rsc.org
The blood–brain barrier (BBB) is a physical structure whose main function is to strictly
regulate access to circulating compounds into the central nervous system (CNS). Vegetable …

Insights into the putative catechin and epicatechin transport across blood-brain barrier

A Faria, D Pestana, D Teixeira, PO Couraud… - Food & function, 2011 - pubs.rsc.org
The identification of mechanisms associated with phenolic neuroprotection is delayed due to
a lack of information regarding the ability of phenolic compounds to enter the central …

Angiotensin‐1‐converting enzyme inhibition, antioxidant activity, and modulation of cerebral Na+/K+ ATPase by free phenolics of African locust bean (Parkia …

K Komolafe, AC Akinmoladun… - Health Science …, 2018 - Wiley Online Library
Aims To investigate the antioxidant activities and effects of free phenols (FPPB) and bound
phenols (BPPB) of Parkia biglobosa leaves on some enzymes of neuro‐cardiovascular …

Neuroprotective effects of agri-food by-products rich in phenolic compounds

A Rojas-García, Á Fernández-Ochoa, ML Cádiz-Gurrea… - Nutrients, 2023 - mdpi.com
Neurodegenerative diseases are known for their wide range of harmful conditions related to
progressive cell damage, nervous system connections and neuronal death. These …

Potential for brain accessibility and analysis of stability of selected flavonoids in relation to neuroprotection in vitro

L Pogačnik, K Pirc, I Palmela, M Skrt, KS Kim, D Brites… - Brain research, 2016 - Elsevier
Natural food sources constitute a promising source of new compounds with neuroprotective
properties, once they have the ability to reach the brain. Our aim was to evaluate the brain …