Heart diseases are one of the leading causes of death for humans in the world. Increasing
evidence has shown that myocardial injury induced innate and adaptive immune responses …

The adult mammalian heart displays negligible regenerative capacity. Therefore, myocardial
infarction (MI) often results in an irreversible loss of contractile tissue, leading to a …

A large body of evidence produced during decades of research indicates that myocardial
injury activates innate immunity. On the one hand, innate immunity both aggravates …

Immediately after cardiac injury, the immune system plays major roles in repair and
regeneration as it becomes involved in a number of processes including damage …

Objective: Lymphatics play an essential pathophysiological role in promoting fluid and
immune cell tissue clearance. Conversely, immune cells may influence lymphatic function …

The burden of heart failure (HF), developing after myocardial infarction MI, still represents a
major issue in clinical practice. Failure of appropriate resolution of inflammation during post …

Cardiac injury triggers an acute immune response that drives tissue healing and remodeling
via the activation of compensatory mechanisms. Over time, remodeling and inflammation …

Growing evidence indicates that overactivation and prolongation of the inflammatory
response after acute myocardial infarction (AMI) result in worse left ventricular remodelling …

Abstract Purpose of Review Immune cells are emerging as central cellular components of
the heart which communicate with cardiac resident cells during homeostasis, cardiac injury …

Despite the advances that have been made in developing new therapeutics, cardiovascular
disease remains the leading cause of worldwide mortality. Therefore, understanding the …