Based on extensive experimental studies, a huge number of phytochemicals showed
potential activity against tuberculosis (TB) at a lower minimum inhibitory concentration (MIC) …

Developing effective inhibitors against Mycobacterium tuberculosis (Mtb) is a challenging
task, primarily due to the emergence of resistant strains. In this study, we have proposed and …

Background: The increasing incidence of multidrug-resistant cases of tuberculosis (TB) and
difficulty in treating these cases requires an urgent need to find an effective anti-TB drug …

The purpose of this study was to provide a number of diverse and promising early-lead
compounds that will feed into the drug discovery pipeline for developing new antitubercular …

Increased numbers of reported cases of Mycobacterium tuberculosis (Mtb) resistance to the
generally used antibiotics demand to identify novel therapeutic entities for better control of …

Aspartate-semialdehyde dehydrogenase (ASADH) of DAP/lysine pathway plays a crucial
role in sustainable growth and pathogenicity of Mycobacterium tuberculosis (Mtb) via …

Background Tuberculosis (TB) is the second leading cause of death from a single infectious
organism, demanding attention towards discovery of novel anti-tubercular compounds …

Abstract Objective Mycobacterium tuberculosis (Mtb) infection is quickly countered by the
host immune system; but, the pathogen is never eradicated. In this infection, 10% of …

Tuberculosis (TB) is a recurrent and progressive disease, with high mortality rates
worldwide. The drug-resistance phenomenon of Mycobacterium tuberculosis is a major …

Tuberculosis (TB) is the foremost cause of infectious fatality globally. The primary global
challenge in combatting TB lies in addressing the emergence of drug-resistant variants of …