Combinatory Nanovesicle with siRNA-Loaded Extracellular Vesicle and IGF-1 for Osteoarthritis Treatments
JY Kim, SY Lee, SG Cha, JM Park, DH Song… - International Journal of …, 2024 - mdpi.com
Extracellular vesicles (EVs) have been found to have the characteristics of their parent cells.
Based on the characteristics of these EVs, various studies on disease treatment using …
Based on the characteristics of these EVs, various studies on disease treatment using …
[HTML][HTML] Dual-engineered cartilage-targeting extracellular vesicles derived from mesenchymal stem cells enhance osteoarthritis treatment via miR-223/NLRP3 …
W Liu, A Liu, X Li, Z Sun, Z Sun, Y Liu, G Wang… - Bioactive Materials, 2023 - Elsevier
Osteoarthritis (OA) is the most common disabling joint disease with no effective disease
modifying drugs. Extracellular vesicles released by several types of mesenchymal stem cells …
modifying drugs. Extracellular vesicles released by several types of mesenchymal stem cells …
A novel extracellular vesicles production system harnessing matrix homeostasis and macrophage reprogramming mitigates osteoarthritis
T Wang, H Zhao, Y Zhang, Y Liu, J Liu, G Chen… - Journal of …, 2024 - Springer
Osteoarthritis (OA) is a degenerative disease that significantly impairs quality of life. There is
a pressing need for innovative OA therapies. While small extracellular vesicles (sEVs) show …
a pressing need for innovative OA therapies. While small extracellular vesicles (sEVs) show …
Anti-inflammatory and immunomodulatory effects of the extracellular vesicles derived from human umbilical cord mesenchymal stem cells on osteoarthritis via M2 …
K Li, G Yan, H Huang, M Zheng, K Ma, X Cui… - Journal of …, 2022 - Springer
Osteoarthritis (OA) is a degenerative illness that greatly impacts the life quality of patients.
Currently, the therapeutic approaches for OA are very limited in clinical. The extracellular …
Currently, the therapeutic approaches for OA are very limited in clinical. The extracellular …
Cartilage progenitor cells derived extracellular vesicles-based cell-free strategy for osteoarthritis treatment by efficient inflammation inhibition and extracellular matrix …
K Feng, F Wang, H Chen, R Zhang, J Liu, X Li… - Journal of …, 2024 - Springer
Osteoarthritis (OA) is a common degenerative joint disease which currently lacks of effective
agents. It is therefore urgent and necessary to seek an effective approach that can inhibit …
agents. It is therefore urgent and necessary to seek an effective approach that can inhibit …
[HTML][HTML] Wharton's jelly mesenchymal stem cell-derived small extracellular vesicles as natural nanoparticles to attenuate cartilage injury via microRNA regulation
P Chen, S Tang, H Gao, H Zhang, C Chen… - International Journal of …, 2022 - Elsevier
The main strategy of tissue repair and regeneration focuses on the application of
mesenchymal stem cells and cell-based nanoparticles, but there are still multiple challenges …
mesenchymal stem cells and cell-based nanoparticles, but there are still multiple challenges …
The potential therapeutic role of extracellular vesicles in osteoarthritis
Y Zhuang, S Jiang, C Yuan, K Lin - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Osteoarthritis (OA) is a worldwide and disabling disease, which cause severe pain and
heavy socioeconomic burden. However, pharmacologic or surgical therapies cannot …
heavy socioeconomic burden. However, pharmacologic or surgical therapies cannot …
A novel approach in biomedical engineering: The use of polyvinyl alcohol hydrogel encapsulating human umbilical cord mesenchymal stem cell-derived exosomes for …
L He, H Zhang, N Zhao, L Liao - International Journal of Biological …, 2024 - Elsevier
Developing effective methods for alveolar bone defect regeneration is a significant
challenge in orthopedics. Exosomes from human umbilical cord mesenchymal stem cells …
challenge in orthopedics. Exosomes from human umbilical cord mesenchymal stem cells …
Engineering exosomes derived from subcutaneous fat MSCs specially promote cartilage repair as miR-199a-3p delivery vehicles in Osteoarthritis
S Zhao, G Xiu, J Wang, Y Wen, J Lu, B Wu… - Journal of …, 2023 - Springer
Osteoarthritis (OA) is a degenerative joint disease involving cartilage. Exosomes derived
from Mesenchymal stem cells (MSCs) therapy improves articular cartilage repair, but …
from Mesenchymal stem cells (MSCs) therapy improves articular cartilage repair, but …
Co-culture engineering: a promising strategy for production of engineered extracellular vesicle for osteoarthritis treatment
A Esmaeili, S Hosseini… - Cell Communication and …, 2024 - Springer
The therapeutic effects of extracellular vesicles (EVs) have been identified as a significant
factor in intercellular communication in different disease treatments, including osteoarthritis …
factor in intercellular communication in different disease treatments, including osteoarthritis …
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