Increasing evidence shows that antigen-presenting cells (APCs) are involved in the
development of inflammation associated to hypertension. However, the potential role of …

Recent studies have emphasized a role of adaptive immunity, and particularly T cells, in the
genesis of hypertension. We sought to determine the T-cell subtypes that contribute to …

Activation of type 1 angiotensin (AT1) receptors causes hypertension, leading to progressive
kidney injury. AT1 receptors are expressed on immune cells, and previous studies have …

Background: Type 1 angiotensin (AT1) receptors are expressed on immune cells, and we
previously found that bone marrow–derived AT1 receptors protect against Ang (angiotensin) …

Cholinergic receptor activation leads to premature development of hypertension and
infiltration of proinflammatory CD161a+/CD68+ M1 macrophages into the renal medulla …

Rationale: The ubiquitin-editing protein A20 in dendritic cells (DCs) suppresses NF-κB
(nuclear factor-κB) signaling and constrains DC-mediated T-cell stimulation, but the role of …

290 Hypertension August 2016 pressure elevation. Moreover, hypertension emerges in
autoimmune disorders such as systemic lupus erythematosus, and blocking inflammatory …

Activation of the immune system by ANG II contributes to the pathogenesis of hypertension,
and pharmacological suppression of lymphocyte responses can ameliorate hypertensive …

Hypertension promotes atherosclerosis and is a major source of morbidity and mortality. We
show that mice lacking T and B cells (RAG-1−/− mice) have blunted hypertension and do not …

Renal immune cell infiltration and cells expressing angiotensin II (AII) in tubulointerstitial
areas of the kidney are features of experimental models of salt-sensitive hypertension …