Advances in high-throughput sequencing over the past decades have led to the
identification of thousands of non-coding RNAs (ncRNAs), which play a major role in …

Antisense transcription is a widespread phenomenon in mammalian genomes, leading to
production of RNAs molecules referred to as natural antisense transcripts (NATs). NATs …

The recent discovery of vast non-coding RNA-based regulatory networks that can be easily
modulated by nucleic acid-based drugs has opened numerous new therapeutic possibilities …

Natural antisense transcripts (NATs), which are transcribed from opposite strands of DNA
with partial or complete overlap, affect multiple stages of gene expression, from epigenetic to …

Long non-coding RNAs (lncRNAs) are emerging as a major class of gene products that
have central roles in cell and developmental biology. Natural antisense transcripts (NATs) …

The vertebrate genome contains large spans of non-coding RNA, which for the most part
were considered of little functional value to the organism. Recent studies have indicated that …

In recent years, natural antisense transcripts (NATs) have been implicated in many aspects
of eukaryotic gene expression including genomic imprinting, RNA interference, translational …

NATs (natural antisense transcripts) are widespread in eukaryotic genomes. Experimental
evidence indicates that sense and antisense transcripts interact, suggesting a role for NATs …

Natural antisense transcripts (NATs) are RNA molecules that originate from opposite DNA
strands of the same genomic locus (cis-NAT) or unlinked genomic loci (trans-NAT). NATs …

Many genomic loci contain transcription units on both strands, therefore two oppositely
oriented transcripts can overlap. Often, one strand codes for a protein, whereas the transcript …