[PDF][PDF] Clinical significance of cytogenetics in acute leukemias

J Shah, K Theil, M Kalaycio - Laboratory Medicine, 2003 - scholar.archive.org
TdT, and HLA. 22 Acute myeloid leukemia M4 with CBFβ-MYH11 has also been reported to
express CD34 and CD117. 23 Several reports have demonstrated that a number of AML-M4 …

Comparison of cytogenetic and molecular genetic detection of t (8; 21) and inv (16) in a prospective series of adults with de novo acute myeloid leukemia: a Cancer …

K Mrózek, TW Prior, C Edwards, G Marcucci… - Journal of Clinical …, 2001 - ascopubs.org
PURPOSE: To prospectively compare cytogenetics and reverse transcriptase–polymerase
chain reaction (RT-PCR) for detection of t (8; 21)(q22; q22) and inv (16)(p13q22)/t (16; …

Monosomy 21 in two patients with acute nonlymphocytic leukemia

JJ Chang, CJ Liu, JH Liu, TJ Chiou, CH Tzeng… - Cancer genetics and …, 1992 - Elsevier
Among 50 cases of acute nonlymphocytic leukemia (ANLL) with available cytogenetic data
seen in our section since May 1988, two were found to carry a monosomy 21 abnormality …

Trisomy 4: a specific karyotype anomaly in primary and secondary acute myeloid leukemia.

E Weber, H Nowotny, OA Haas, H Kasparu, N Grois… - Leukemia, 1990 - europepmc.org
Trisomy 4 as single karyotype anomaly has recently been proposed as an acute myeloid
leukemia (AML) specific aberration. Up to now, 20 cases have been reported in which the …

Is trisomy 22 in acute myeloid leukemia a primary abnormality or only a secondary change associated with inversion 16?

N Grois, H Nowotny, E Tyl, O Krieger, P Kier… - Cancer genetics and …, 1989 - Elsevier
In an attempt to confirm the existence of acute myeloid leukemia (AML) with trisomy 22, we
studied three patients in whom trisomy 22 imposed as the sole karyotype abnormality. After …

Gain of an isochromosome 5p:: a new recurrent chromosome abnormality in acute monoblastic leukemia

C Schoch, S Bursch, W Kern, S Schnittger… - Cancer genetics and …, 2001 - Elsevier
In acute myeloid leukemia (AML) close associations are known between cytomorphology
and cytogenetics such as in AML M3/M3v showing at (15; 17) and in AML M4eo associated …

The clinical use of cytogenetics in acute leukemia

MR Baer, CD Bloomfield - Annals of medicine, 1991 - Taylor & Francis
(FAB M4Eo) was in fact defined on the basis of chromosomal abnormalities involving 16q22,
including inv (l6)(pl3q22), t (16; 16)(pl3; q22) and del (l6)(q22). Other cytogenetic …

Tetrasomy 21 as the sole acquired karyotypic abnormality in acute myeloblastic leukemia

T Odagaki, T Sugimoto, M Matsuo, E Tatsumi… - Cancer genetics and …, 2001 - Elsevier
Peripheral blood and bone marrow analysis of a 79-year-old female led to a diagnosis of
acute myeloblastic leukemia with differentiation (AML-M2). Chromosome analysis of the …

Is trisomy 4 a secondary chromosomal abnormality in acute myeloblastic leukemia?

R Bonomi, M Le Coniat, R Berger - Cancer genetics and cytogenetics, 1995 - Elsevier
Cytogenetic studies were carried out in a patient with acute monocytic leukemia (AML-M5) at
diagnosis and in relapse. While no chromosome abnormality was detected initially, isolated …

Acute myeloid leukemia (AML-M1) with multiple trisomies and t (8; 21)(q22; q22)

M Köhler, B Johansson, J Ludvigsson, P Åman… - Cancer genetics and …, 1994 - Elsevier
Cytogenetic analysis of an acute myeloid leukemia (AML-M1) showed the karyotype 53,
XY,+ 6,+ 8, t (8; 21)(q22; q22),+ 9,+ 10,+ 13,+ 19,+ 21. Only one AML with a massively …