'Under pressure': The role of therapeutic drug monitoring in the treatment of hypertension

J Versmissen, J van Steenkiste… - British Journal of …, 2024 - Wiley Online Library
Antihypertensive drugs do not qualify as optimal candidates for therapeutic drug monitoring
(TDM), given their obvious physiological effect, the absence of a clear relationship between …

Adherence to antihypertensive therapy and therapeutic dosage of antihypertensive drugs

F Rabbia, C Fulcheri, S Di Monaco, M Covella… - High Blood Pressure & …, 2016 - Springer
Adherence to antihypertensive therapy is critical to achieving adequate blood pressure
control. About half of hypertensive patients do not take their drugs as directed and the …

Therapeutic drug monitoring‐guided definition of adherence profiles in resistant hypertension and identification of predictors of poor adherence

V Avataneo, A De Nicolò, F Rabbia… - British journal of …, 2018 - Wiley Online Library
Aims Arterial hypertension is an important cardiovascular risk factor. A substantial proportion
of patients show resistance to antihypertensive treatment but poor adherence to medication …

[HTML][HTML] Identifying poor adherence to antihypertensive medications in patients with resistant hypertension

IS Mackenzie, TM MacDonald - British journal of clinical …, 2019 - ncbi.nlm.nih.gov
Poor adherence (compliance) to antihypertensive medications is a major contributor to
morbidity and mortality in patients with hypertension. Estimates in the literature of the extent …

How to screen for non-adherence to antihypertensive therapy

P Gupta, P Patel, R Horne, H Buchanan… - Current hypertension …, 2016 - Springer
The quality of assessment of non-adherence to treatment in hypertensive is poor. Within this
review, we discuss the different methods used to assess adherence to blood-pressure …

Detecting nonadherence to antihypertensive treatment: any time, anywhere?

I Hamdidouche, V Jullien, S Laurent, M Azizi - Hypertension, 2017 - Am Heart Assoc
258 Hypertension August 2017 other than hypertension,(2) BP measurements in this setting
do not reflect the ambulatory BP profiles of these patients,(3) information about the precise …

The effect of combining therapeutic drug monitoring of antihypertensive drugs with personalised feedback on adherence and resistant hypertension: the (RHYME-RCT …

LEJ Peeters, MHW Kappers, E Boersma… - BMC Cardiovascular …, 2023 - Springer
Background Adherence to antihypertensive drugs (AHDs) is important for adequate blood
pressure control. Not taking these drugs as prescribed is one of the main underlying causes …

Establishing serum reference ranges for antihypertensive drugs

S Rognstad, CL Søraas, OU Bergland… - Therapeutic Drug …, 2021 - journals.lww.com
Background: Therapeutic drug monitoring (TDM) involves the measurement of serum drug
concentrations to optimize pharmacotherapy. Traditionally, blood pressure measurements …

Effect of Therapeutic Drug Monitoring on Adherence and Blood Pressure: A Multicenter Randomized Clinical Trial

LV Halvorsen, CL Søraas, ACK Larstorp… - American Journal of …, 2024 - academic.oup.com
BACKGROUND Drug concentration in blood or urine is an acknowledged method to detect
non-adherence. Observational studies suggest that informing patients about low or absent …

Plasma trough concentrations of antihypertensive drugs for the assessment of treatment adherence: a meta-analysis

EH Groenland, MEAM van Kleef, ML Bots… - …, 2021 - Am Heart Assoc
Biochemical drug screening by liquid chromatography-tandem mass spectrometry in plasma
is an accurate method for the quantification of plasma concentrations of antihypertensive …