Context Plantamajoside (PMS) possesses rich pharmacological characteristics that have
been applied to remedy dozens of diseases. However, the understanding of PMS in sepsis …

Oxymatrine (OMT), which is a quinolizidine alkaloid extracted from the traditional Chinese
herb Sophora flavescens Aiton, is often used to treat various inflammatory diseases. The …

Despite developments in the knowledge and therapy of acute lung injury in recent decades,
mortality remains high, and there is usually a lack of effective therapy. Plantamajoside, a …

Sepsis is a life‐threatening organ dysfunction that endangers patient lives and is caused by
an imbalance in the host defense against infection. Sepsis continues to be a significant …

Sepsis is a life-threatening organ dysfunction associated with macrophage overactivation.
Targeted therapy against macrophages is considered a promising strategy for sepsis …

Puerarin, an isoflavonoid rich in Radix Puerariae, has been reported to be a broadly
effective regulator in various biological processes and clinic conditions. However, the role of …

Sepsis caused by Gram-negative bacteria is one of major causes for the progression of
acute lung injury (ALI) with limited treatment and effective medicines. Tabersonine is an …

Background Sepsis is defined as life-threatening organ dysfunction caused by a
dysregulated host response to infection. Abnormal activation of NOD-like receptor thermal …

Current evidence shows that the majority of the damage induced during sepsis is pursuant
to induction and overproduction of endogenous cytokines. Embelin has been reported to …

Oxymatrine is a traditional Chinese herbal product that exhibits anti-inflammatory effects in
models of heart, brain and liver injury. We investigated the impact of oxymatrine in an acute …