A three-dimensional (3D) lung aggregate model based on sodium alginate scaffolds was
developed to study the interactions between Paracoccidioides brasiliensis (Pb) and lung …

Aspergillus fumigatus is the most reported causative pathogen associated with the
increasing global incidences of aspergilloses, with the health of immunocompromised …

Fungal infections (mycoses) affect over a billion people per year. Approximately, two million
of these infections are life-threatening, especially for patients with a compromised immune …

To study interactions of airborne pathogens, eg Aspergillus (A.) fumigatus with upper and
lower respiratory tract epithelial and immune cells, we set up a perfused 3D human …

Paracoccidioides species are dimorphic fungi that initially infect the lungs but can also
spread throughout the body. The spreading infection is most likely due to the formation of a …

Candida albicans is a commensal yeast of the human intestinal microbiota that, under
predisposing conditions, can become pathogenic and cause life-threatening systemic …

Fungi that belong to the genus Paracoccidioides are the etiologic agents of
paracoccidioidomycosis, a human systemic mycosis, which occurs in Latin America …

Using the intraperitoneal route of infection, we demonstrated previously that A/Sn mice are
resistant and B10. A mice are susceptible to Paracoccidioides brasiliensis infection. Since …

Paracoccidioides species are dimorphic fungi that initially infect the lungs but can also
spread throughout the body. The spreading infection is most likely due to the formation of a …

Highlights•The increased incidence of human fungal infections is related to immune
disorders.•Humans are 'holobionts', maintaining balanced interactions with pathobionts and …