Glutathione S-transferases (GSTs) are phase II drug detoxifying enzymes that play an
essential role in the maintenance of cell integrity and protection against DNA damage by …

Glutathione S-transferases (GSTs) are phase II detoxifying enzymes involved in the
maintenance of cell integrity, oxidative stress and protection against DNA damage by …

Abstract Glutathione‐S‐transferases (GSTs) are metabolic enzymes that help detoxify and
eliminate harmful chemicals. In prostate tumors, expression of GST π (encoded by GSTP1) …

Importance of the field: The Glutathione S-transferases (GSTs) have advanced beyond the
classic view of their role in metabolism and are encouraging scientists to assess new …

The pi‐class glutathione S‐transferase (GSTP1) actively protect cells from carcinogens and
electrophilic compounds. Loss of GSTP1 expression via promoter hypermethylation is the …

Among the many somatic genome alterations present in cancer cells, changes in DNA
methylation may represent reversible “epigenetic” lesions, rather than irreversible “genetic” …

Abstract Glutathione S-transferase P1 (GSTP1) is of importance for cancer research
because of its role in detoxifying carcinogens, activating antineoplastic prodrugs …

Abstract Glutathione-S-Transferases (GSTs) comprise a family of isoenzymes that provide
protection to mammalian cells against electrophilic metabolites of carcinogens and reactive …

Abstract Glutathione S-transferase P (GSTP) is one member of the GST superfamily that is
prevalently expressed in mammals. Known to possess catalytic activity through …

Somatic hypermethylation of CpG island sequences at GSTP1, the gene encoding the π‐
class glutathione S‐transferase, appears to be characteristic of human prostatic …