Mapping epistatic quantitative trait loci with one-dimensional genome searches

JL Jannink, R Jansen - Genetics, 2001 - academic.oup.com
The discovery of epistatically interacting QTL is hampered by the intractability and low power
to detect QTL in multidimensional genome searches. We describe a new method that maps …

Controlling false positives in the mapping of epistatic QTL

WH Wei, S Knott, CS Haley, DJ De Koning - Heredity, 2010 - nature.com
This study addresses the poorly explored issue of the control of false positive rate (FPR) in
the mapping of pair-wise epistatic quantitative trait loci (QTL). A nested test framework was …

Assessment of DNA pooling strategies for mapping of QTLs

GL Wang, AH Paterson - Theoretical and Applied Genetics, 1994 - Springer
The synthesis of “DNA pools” from segregating populations is an efficient strategy for
identifying DNA markers closely linked to genes or genomic regions of interest. To-date …

QTL mapping using high-throughput sequencing

TM Jamann, PJ Balint-Kurti, JB Holland - Plant functional genomics …, 2015 - Springer
Quantitative trait locus (QTL) mapping in plants dates to the 1980s (Stuber et al. Crop Sci 27:
639–648, 1987; Paterson et al. Nature 335: 721–726, 1988), but earlier studies were often …

QTL analysis in plants; where are we now?

MJ Kearsey, AGL Farquhar - Heredity, 1998 - nature.com
We have briefly reviewed the methods currently available for QTL analysis in segregating
populations and summarized some of the conclusions arising from such analyses in plant …

Use of randomization testing to detect multiple epistatic QTLs

Ö Carlborg, L Andersson - Genetics Research, 2002 - cambridge.org
Here, we describe a randomization testing strategy for mapping interacting quantitative trait
loci (QTLs). In a forward selection strategy, non-interacting QTLs and simultaneously …

Combining different line crosses for mapping quantitative trait loci using the identical by descent-based variance component method

C Xie, DDG Gessler, S Xu - Genetics, 1998 - academic.oup.com
Mapping quantitative trait loci (QTLs) is usually conducted with a single line cross. The
power of such QTL mapping depends highly on the two parental lines. If the two lines are …

Combining data from multiple inbred line crosses improves the power and resolution of quantitative trait loci mapping

R Li, MA Lyons, H Wittenburg, B Paigen… - Genetics, 2005 - academic.oup.com
Rodent inbred line crosses are widely used to map genetic loci associated with complex
traits. This approach has proven to be powerful for detecting quantitative trait loci (QTL); …

Comparison of mixed-model approaches for association mapping in rapeseed, potato, sugar beet, maize, and Arabidopsis

B Stich, AE Melchinger - BMC genomics, 2009 - Springer
Background In recent years, several attempts have been made in plant genetics to detect
QTL by using association mapping methods. The objectives of this study were to (i) evaluate …

Analytical approaches and population types for finding and utilizing QTL in complex plant populations

CH Sneller, DE Mather, S Crepieux - Crop science, 2009 - Wiley Online Library
In the past decade plant geneticists began using complex plant populations to identify QTL
by association analysis, and the practice is becoming commonplace. Plant populations …