Cardiac ischemia–reperfusion (I/R) injury results mainly from mitochondrial dysfunction and
cardiomyocyte death. Mitophagy sustains mitochondrial function and exerts a pro-survival …

Background Post-infarction cardiac injury is closely associated with cardiac remodeling and
heart dysfunction. Mammalian STE20-like kinase 1 (Mst1), a regulator of cellular apoptosis …

Cardiomyocyte function and viability are highly modulated by mammalian Ste20‐like kinase
1 (Mst1)‐Hippo pathway and mitochondria. Mitophagy, a kind of mitochondrial autophagy, is …

LPS-induced septic cardiomyopathy has been found to be connected with mitochondrial
stress through unknown mechanisms. Mitochondrial fission is an early event in …

Disturbed mitochondrial homeostasis contributes to the pathogenesis of cardiac ischemia
reperfusion (IR) injury, although the underlying mechanism remains elusive. Here, we …

Mitochondrial dysfunction contributes to heart failure induced mortality in approximately 80%
of diabetic patients. Mitophagy degrades defective mitochondria and maintains a healthy …

Background/Aims: The aim of our study is to investigate the molecular mechanism by which
mammalian STE20-like kinase 1 (Mst1) participates in renal I/R injury through modifying …

Abstract Aims Angiotension II (Ang II) plays a central role in the pathogenesis of renin-
angiotensin-aldosterone system (RAAS)-induced heart failure. Mst1 exerts its function in …

Despite extensive research that has been carried out over the past three decades in the field
of renal ischaemia-reperfusion (I/R) injury, the pathogenic role of mitochondrial fission in …

Apoptosis is associated with various myocardial diseases. Angiotensin II (Ang II) plays a
central role in the pathogenesis of RAAS‐triggered cardiac apoptosis. Our previous studies …